Evidence map›Paper›PMID 31564857›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2019

Yipeng Ding, Quanni Li, Qiong Feng, Dongchuan Xu, Cibing Wu, Jie Zhao, Xiaoli Zhou, Yixiu Yang, Huan Niu, Ping He and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yipeng Ding *Department of General Practice, Hainan General Hospital, Haikou, Hainan 570311, People's Republic of China.
Quanni Li *Department of General Practice, Hainan General Hospital, Haikou, Hainan 570311, People's Republic of China.
Qiong FengHainan General Hospital, University of South China, Haikou, Hainan 570311, People's Republic of China.
Dongchuan XuDepartment of General Practice, Hainan General Hospital, Haikou, Hainan 570311, People's Republic of China.
Cibing WuHainan General Hospital, University of South China, Haikou, Hainan 570311, People's Republic of China.
Jie ZhaoHainan General Hospital, University of South China, Haikou, Hainan 570311, People's Republic of China.
Xiaoli ZhouDepartment of General Practice, Hainan General Hospital, Haikou, Hainan 570311, People's Republic of China.
Yixiu YangDepartment of General Practice, Hainan General Hospital, Haikou, Hainan 570311, People's Republic of China.
Huan NiuDepartment of General Practice, Hainan General Hospital, Haikou, Hainan 570311, People's Republic of China.
Ping HeDepartment of General Practice, Hainan General Hospital, Haikou, Hainan 570311, People's Republic of China.
Lihua XingDepartment of Respiratory Intensive Care Unit (RICU), The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 45000, People's Republic of China.
Hainan General Hospital · CNFirst Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chronic obstructive pulmonary disease (COPD) is a lung disease closely related to exposure to exogenous substances. Materials and methods: Genotypes of the five candidate SNPs in Results: In allele model, we observed that rs4803420 G and rs1038376 A were related to COPD risk. And rs4803420 G/T and G/T-T/T were related to a decreased COPD risk compared to GG genotype in the co-dominant and dominant models, respectively. When comparing with the AA genotype, rs1038376 A/T and A/T-T/T were associated with an increased COPD risk in the co-dominant and dominant models, respectively. Further gender stratification co-dominant and dominant models analysis showed that genotype G/T and G/T-T/T of rs4803420, and genotype A/T and A/T-T/T of rs1038376 were significantly associated with COPD risk compared to the wide type in males and females, while allele C of rs12979270 was only associated with COPD risk in females. Smoking status stratification analysis showed that rs12979270 C was significantly associated with an increased COPD risk under the allele model compared with allele A in the smoking subgroup. Haplotype analysis showed that haplotype GTA and TAA were related to COPD risk. Conclusion: Our data is the first to demonstrate that

Indexed as

Polymorphism, Single NucleotideAgedAsian PeopleCase-Control StudiesChinaCytochrome P-450 CYP2B6FemaleGene FrequencyGenetic Association StudiesGenetic Predisposition to DiseaseHaplotypesHumansMaleMiddle AgedPhenotypePulmonary Disease, Chronic ObstructiveCYP2B6 protein, humanCytochrome P-450 CYP2B6case–control studychronic obstructive pulmonary diseaseCOPDCYP2B6gene polymorphisms

Identifiers

PMID31564857
PMCPMC6733340
OpenAlexW2971447047

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.