ArticlePatient preference and adherence2019
Adherence to long-term therapies in cystic fibrosis: a French cross-sectional study linking prescribing, dispensing, and hospitalization data.
Article in Patient preference and adherence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Medication adherence to CFTR modulators in patients with cystic fibrosis: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2024Pooled it
- Associations Between Socioeconomic Status and Adherence to Medications in People With Cystic Fibrosis.Pediatric pulmonology · 2025Article
- Using Community Engagement to Create a Telecoaching Intervention to Improve Self-Management in Adolescents and Young Adults With Cystic Fibrosis: Qualitative Study.Journal of participatory medicine · 2025Article
- Determinants of adherence to post-stroke/transient ischemic attack secondary prevention medications: A cohort study.European journal of neurology · 2024Article
- The ageing of people living with cystic fibrosis: what to expect now?European respiratory review : an official journal of the European Respiratory Society · 2024Review
- Considerations for the use of inhaled antibiotics forBMJ open respiratory research · 2024Article
- Improving health literacy of antibiotic use in people with cystic fibrosis (CF)-comparison of the readability of patient information leaflets (PILs) from the EU, USA and UK of 23 CF-related antibiotics used in the treatment of CF respiratory infections.JAC-antimicrobial resistance · 2023Article
- A Participatory Approach Involving Patients with Cystic Fibrosis and Healthcare Professionals for the Co-Design of an Adherence-Enhancing Intervention Toolkit.Patient preference and adherence · 2023Article
- Use of mucoactive agents in cystic fibrosis: A consensus survey of Italian specialists.Health science reports · 2022Review
- Use of inhaled antibiotics among Danish patients with cystic fibrosis.Pediatric pulmonology · 2022Article
- Survey and electronic health record-based medication use agreement in children with cystic fibrosis: A retrospective cross-sectional study.International journal of paediatric dentistry · 2021Article
- Article
- Making the invisible visible: the availability and desirability of adherence data in routine CF care- findings from a national questionnaire survey.F1000Research · 2019Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCystic fibrosis (CF) is a life-shortening genetic condition that usually affects several organs and involves significant treatment burden. Adherence to medication is important for successful CF management.
objectiveTo describe medication adherence according to age, therapeutic class, and pharmaceutical form in adults and children followed in four regional CF centers in France.
methodsWe conducted a cross-sectional study with non-transplanted patients followed in two adult and two pediatric centers during 2015 who were covered by the French National Health Insurance (NHI). Sociodemographic, clinical, hospitalization, and prescription data were collected from patient medical records. Medication dispensations were extracted from the regional French NHI database. Adherence was calculated over 12 months using continuous medication availability (CMA) accounting for dose adjustments and hospitalizations. Drug-specific CMA was computed in R with the AdhereR package for each medication prescribed more than 3 months, which was averaged to obtain a composite CMA score (cCMA) for all treatments and per therapeutic class as well as pharmaceutical form for each patient.
resultsA total of 228 patients were included. The number of chronic medications increased with age (
conclusionThis study suggests that adherence to medication regimens in CF patients remains suboptimal and varies substantially between age groups and pharmaceutical forms. These variations in adherence should be considered when developing effective strategies to improve adherence.
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