Evidence map›Paper›PMID 31564451›Full record

Trial reportVaccine2019

Home-based records and vaccination appointment stickers as parental reminders to reduce vaccination dropout in Indonesia: A cluster-randomized controlled trial.

Aaron S Wallace, Kenny Peetosutan, Andi Untung, Marisa Ricardo, Prima Yosephine, Kathleen Wannemuehler, David W Brown, Deborah A McFarland, Walter A Orenstein, Eli S Rosenberg and 2 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Vaccine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Aaron S WallaceDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, United States; Global Immunization Division, United States Centers for Disease Control and Prevention, Atlanta, GA, 30333, United States. Electronic address: awallace@cdc.gov.
Kenny PeetosutanMaternal and Child Health Team, UNICEF, Jakarta, Indonesia.
Andi UntungHealth Communications Team, Ministry of Health, Jakarta, Indonesia.
Marisa RicardoMaternal and Child Health Team, UNICEF, Addis Ababa, Ethiopia.
Prima YosephineNational Immunization Program, Ministry of Health, Jakarta, Indonesia.
Kathleen WannemuehlerGlobal Immunization Division, United States Centers for Disease Control and Prevention, Atlanta, GA, 30333, United States.
David W BrownBrown Consulting Group International LLC, Cornelius, NC, 28031, United States.
Deborah A McFarlandDepartment of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, United States.
Walter A OrensteinDivision of Infectious Diseases, School of Medicine, Emory University, Atlanta, GA 30322, United States.
Eli S RosenbergDepartment of Epidemiology and Biostatistics, School of Public Health, University at Albany, State University of New York, Albany 12222, United States.
Saad B OmerDepartment of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, United States.
Danni DanielsGlobal Immunization Division, United States Centers for Disease Control and Prevention, Atlanta, GA, 30333, United States.
Centers for Disease Control and Prevention · USEmory University · USMinistry of Health · IDAlbany State University · USJohnson Group Consulting · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Intramural CDC HHS CC999999NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

introductionLimited evidence is available about the effectiveness of strategies to remind caregivers when to bring children back for future vaccinations in low- and middle-income country settings. We evaluated the effectiveness of two reminder strategies based on home-based vaccination records (HBR) in Indonesia.

methodsIn this cluster-randomized controlled trial involving 3616 children <1 year of age, 90 health facilities were randomly assigned to either a control group or one of two intervention groups: (1) HBR-only group, where healthcare workers provided an HBR to any child without an HBR during a vaccination visit and instructed the caregiver to keep it at home between visits, or (2) HBR + sticker group, where, in addition to HBR provision, healthcare workers placed vaccination appointment reminder stickers on the HBR. The primary outcome was receipt of the third dose of diphtheria-tetanus-pertussis-containing vaccine (DTPcv3) within 7 months and the secondary outcome was receipt of a timely DTPcv3 dose.

resultsControl group DTPcv3 coverage was 81%. In intention-to-treat analysis, neither intervention group had significantly different DTPcv3 coverage compared with the control group (RR = 0.94, 95% confidence interval [CI] 0.87; 1.02 for HBR-only group; RR = 0.97, 95% CI 0.90; 1.04 for HBR + sticker group) by study end. However, children in the HBR + sticker group were 50% more likely to have received a DTPcv3 vaccination (RR = 1.46, 95% CI 1.02, 2.09) within 60 days of DTPcv1 vaccination, compared with children in the control group; children in the HBR-only group were not more likely to have done so (RR = 1.05, 95% CI 0.71, 1.55). DISCUSSION: Reminder stickers had an immediate effect on coverage by improving the proportion of children who received a timely DTPcv3 dose but no effect on the proportion who received DTPcv3 after 7 months. Coupling reminder stickers with strategies to address other reasons why children do not return for vaccination visits should be further explored.

Indexed as

Appointments and SchedulesCaregiversFemaleHealth PersonnelHumansImmunizationIndonesiaInfantInfant, NewbornMaleParentsReminder SystemsVaccinationIndonesiaVaccinationVaccination reminder

Identifiers

PMID31564451
PMCPMC7005856
OpenAlexW2976070872

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.