Evidence map›Paper›PMID 31564203›Full record

ArticleCell cycle (Georgetown, Tex.)2019

MicroRNA-129-5p alleviates nerve injury and inflammatory response of Alzheimer's disease via downregulating SOX6.

Zhilei Zeng, Yajun Liu, Wei Zheng, Liubin Liu, Honglei Yin, Simiao Zhang, Hongying Bai, Linlin Hua, Shanshan Wang, Zhen Wang and 4 more

RetractedOpen access · bronzeAbstract readRetracted Publication
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Autophagy and apoptosis cascade: which is more prominent in neuronal death?Cellular and molecular life sciences : CMLS · 2021
    Review
  12. Role of microRNA-129 in cancer and non-cancerous diseases (Review).Experimental and therapeutic medicine · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. The Journal of international medical research · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Zhilei ZengDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Yajun LiuDepartment of Neurology, The 960th PLA hospital , Zibo , shandong , China.
Wei ZhengDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Liubin LiuDepartment of Neurology, The 960th PLA hospital , Zibo , shandong , China.
Honglei YinDepartment of Neurology, The 960th PLA hospital , Zibo , shandong , China.
Simiao ZhangDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Hongying BaiDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Linlin HuaDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Shanshan WangDepartment of Neurology, The 960th PLA hospital , Zibo , shandong , China.
Zhen WangDepartment of Neurology, The 960th PLA hospital , Zibo , shandong , China.
Xiaodong LiDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Jianhao XiaoDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Qian YuanDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Yunliang WangDepartment of Neurology, The Second Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Second Affiliated Hospital of Zhengzhou University · CNCentral Hospital of Zibo · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is growing evidence of the position of microRNAs (miRs) in Alzheimer's disease (AD), thus our objective was to discuss the impact of miR-129-5p regulating nerve injury and inflammatory response in AD rats by modulating SOX6 expression. The AD rat model was established by injecting Aβ

Indexed as

Alzheimer DiseaseAnimalsApoptosisbcl-2-Associated X ProteinBehavior Rating ScaleCell ProliferationCells, CulturedDown-RegulationHippocampusInflammationInterleukin-1betaMaleMicroRNAsMicroscopy, ElectronNeuronsProto-Oncogene Proteins c-bcl-2Bax protein, ratbcl-2-Associated X ProteinBcl2 protein, ratIL1B protein, ratInterleukin-1betaMicroRNAsMIRN129 microRNA, ratProto-Oncogene Proteins c-bcl-2RNA, Small InterferingSOXD Transcription FactorsTumor Necrosis Factor-alphaInterleukin-1βMicroRNA-129-5pSOX6

Identifiers

PMID31564203
PMCPMC6816367
OpenAlexW2978143611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.