Evidence map›Paper›PMID 31564195›Full record

ArticleJournal of the American Heart Association2019

Hemodialysis Procedure-Associated Autonomic Imbalance and Cardiac Arrhythmias: Insights From Continuous 14-Day ECG Monitoring.

Nichole M Rogovoy, Stacey J Howell, Tiffany L Lee, Christopher Hamilton, Erick A Perez-Alday, Muammar M Kabir, Yanwei Zhang, Esther D Kim, Jessica Fitzpatrick, Jose M Monroy-Trujillo and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cardiopulmonary Exercise Testing across Interdialytic Intervals in Hemodialysis Patients.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Article
  5. Article
  6. Review
  7. The cardiovascular unphysiology of thrice weekly hemodialysis.Current opinion in nephrology and hypertension · 2025
    Review
  8. Article
  9. Current and Future Use of Artificial Intelligence in Electrocardiography.Journal of cardiovascular development and disease · 2023
    Review
  10. Review
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Nichole M RogovoyOregon Health & Science University Portland OR.
Stacey J HowellOregon Health & Science University Portland OR.
Tiffany L LeeOregon Health & Science University Portland OR.
Christopher HamiltonOregon Health & Science University Portland OR.
Erick A Perez-AldayOregon Health & Science University Portland OR.
Muammar M KabirOregon Health & Science University Portland OR.
Yanwei ZhangOregon Health & Science University Portland OR.
Esther D KimThe Hospital for Sick Children The University of Toronto Ontario Canada.
Jessica FitzpatrickThe Hospital for Sick Children The University of Toronto Ontario Canada.
Jose M Monroy-TrujilloJohns Hopkins University Baltimore MD.
Michelle M EstrellaJohns Hopkins University Baltimore MD.
Stephen M SozioJohns Hopkins University Baltimore MD.
Bernard G JaarJohns Hopkins University Baltimore MD.
Rulan S ParekhThe Hospital for Sick Children The University of Toronto Ontario Canada.
Larisa G TereshchenkoOregon Health & Science University Portland OR.
Oregon Health & Science University · USJohns Hopkins University · USSickKids Foundation · CASan Francisco VA Health Care System · USUniversity of Toronto · CA

Funding

Longitudinal Study of DialysisR01DK072367 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI PAREKH, RULAN S · 2007 to 2011
$3.7M
Novel ECG Measures and Risk of Sudden Cardiac DeathR01HL118277 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TERESHCHENKO, LARISA GENNADIEVNA · 2013 to 2016
$1.5M
Novel ECG measures and risk of sudden cardiac deathR56HL118277 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TERESHCHENKO, LARISA GENNADIEVNA · 2018 to 2018
$396k
NHLBI NIH HHS R01 HL118277NHLBI NIH HHS R56 HL118277NIDDK NIH HHS R01 DK072367
6 · The paper itself

Abstract

Background In patients with end-stage kidney disease, sudden cardiac death is more frequent after a long interdialytic interval, within 6 hours after the end of a hemodialysis session. We hypothesized that the occurrence of paroxysmal arrhythmias is associated with changes in heart rate and heart rate variability in different phases of hemodialysis. Methods and Results We conducted a prospective ancillary study of the Predictors of Arrhythmic and Cardiovascular Risk in End Stage Renal Disease cohort. Continuous ECG monitoring was performed using an ECG patch, and short-term heart rate variability was measured for 3 minutes every hour (by root mean square of the successive normal-to-normal intervals, spectral analysis, Poincaré plot, and entropy), up to 300 hours. Out of enrolled participants (n=28; age 54±13 years; 57% men; 96% black; 33% with a history of cardiovascular disease; left ventricular ejection fraction 70±9%), arrhythmias were detected in 13 (46%). Nonsustained ventricular tachycardia occurred more frequently during/posthemodialysis than pre-/between hemodialysis (63% versus 37%,

Indexed as

Electrocardiography, AmbulatoryHeart RateAdultAgedAutonomic Nervous SystemCircadian RhythmFemaleHeartHumansKidney Failure, ChronicMaleMiddle AgedPredictive Value of TestsProspective StudiesRenal DialysisRisk Factorselectrocardiographyheart rate/heart rate variabilityhemodialysistrigger clustersventricular arrhythmia

Identifiers

PMID31564195
PMCPMC6806026
OpenAlexW2975049272

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.