Evidence map›Paper›PMID 31564191›Full record

ArticleJournal of the American Heart Association2019

Posttraumatic Stress Disorder and Risk for Early Incident Atrial Fibrillation: A Prospective Cohort Study of 1.1 Million Young Adults.

Lindsey Rosman, Rachel Lampert, Christine M Ramsey, James Dziura, Phillip W Chui, Cynthia Brandt, Sally Haskell, Matthew M Burg

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Plasma Cortisol and Risk of Atrial Fibrillation: A Mendelian Randomization Study.The Journal of clinical endocrinology and metabolism · 2021
    Pooled it
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  16. Neuropsychiatry of atrial fibrillation: dementia and beyond.Frontiers in cardiovascular medicine · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Lindsey RosmanDepartment of Medicine-Cardiology University of North Carolina School of Medicine Chapel Hill NC.
Rachel LampertDepartment of Internal Medicine (Cardiovascular Medicine) Yale School of Medicine New Haven CT.
Christine M RamseyYale Center for Medical Informatics Yale School of Medicine New Haven CT.
James DziuraYale Center for Medical Informatics Yale School of Medicine New Haven CT.
Phillip W ChuiDepartment of Internal Medicine (Cardiovascular Medicine) Yale School of Medicine New Haven CT.
Cynthia BrandtDepartment of Emergency Medicine Yale School of Medicine New Haven CT.
Sally HaskellDepartment of Internal Medicine Yale School of Medicine New Haven CT.
Matthew M BurgDepartment of Internal Medicine (Cardiovascular Medicine) Yale School of Medicine New Haven CT.
Yale University · USVA Connecticut Healthcare System · USUniversity of North Carolina at Chapel Hill · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
PTSD, Sleep, and Risk for Incident HypertensionR01HL125587 · NHLBI · YALE UNIVERSITY · PI BURG, MATTHEW M · 2015 to 2018
$3.2M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL125587
6 · The paper itself

Abstract

Background Acute psychological stress and negative emotions are known risk factors for atrial fibrillation (AF). Whether exposure to chronic stress syndromes, such as posttraumatic stress disorder (PTSD), also increases susceptibility to AF is unknown. Methods and Results We prospectively assessed the incidence of AF over a 13-year period among 988 090 young and middle-aged veterans (mean age, 30.29±9.19 years; 87.8% men, 64.5% white) who first accessed care through the Veterans Health Administration from October 2001 to November 2014 and were free of AF, atrial flutter, or atrial tachycardia at baseline. Time-varying, multivariate Cox proportional hazard models were used to examine the independent contribution of PTSD to new AF. We also tested for effect modification by sex and controlled for healthcare use. During a mean follow-up of 4.8 years, 2491 patients were diagnosed with AF. Patients with PTSD had a higher overall incidence of AF (

Indexed as

AdolescentAdultAge FactorsAtrial FibrillationDepressionFemaleHumansIncidenceMaleMiddle AgedPrognosisProspective StudiesRisk AssessmentRisk FactorsStress Disorders, Post-TraumaticTime Factorsarrhythmiasatrial fibrillationposttraumatic stress disorderstress

Identifiers

PMID31564191
PMCPMC6806049
OpenAlexW2975654683

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.