Observational studyJournal of the American Heart Association2019
Association of Adverse Pregnancy Outcomes With Hypertension 2 to 7 Years Postpartum.
Observational study in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02231398 (Pregnancy as a Window to Future Cardiovascular Health), which is not on this map. Cited by 84 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pregnancy as a Window to Future Cardiovascular Health: Adverse Pregnancy Outcomes as Predictors of Increased Risk Factors for Cardiovascular Disease
Who cites it
84 citing papers in PubMed, 1 synthesis or guideline pooled it, 124 citations in OpenAlex.
- Effects of Immediate Postpartum Diuretic Treatment on Postpartum Blood Pressure Among Individuals With Hypertensive Disorders of Pregnancy: A Systematic Review and Meta-Analysis.Hypertension (Dallas, Tex. : 1979) · 2026Pooled it
- A Behavioral Lifestyle Intervention to Limit Gestational Weight Gain in Pregnant Women with Overweight and Obesity.Obesity (Silver Spring, Md.) · 2021Trial
- Adverse pregnancy outcomes, longitudinal change in eGFR, and incident hypertension in women: a population-based cohort study.Renal failure · 2026Article
- Health behavior profiles in early pregnancy are associated with adverse pregnancy outcomes and maternal blood pressure 2-7 years after delivery.American journal of preventive cardiology · 2026Article
- Subtypes of Hypertension 2 to 7 Years After First Pregnancy.Hypertension (Dallas, Tex. : 1979) · 2026Observational
- Racial Differences in Adverse Pregnancy Outcomes and Incident Hypertension: A Mediation Analysis.Journal of the American Heart Association · 2026Article
- Machine learning-based risk assessment of neonatal perinatal adverse outcomes of anemia during pregnancy: a modeling study.BMC medical informatics and decision making · 2026Article
- Large-scale proteomics in early pregnancy and timing of onset of hypertensive disorders of pregnancy.medRxiv : the preprint server for health sciences · 2026Article
- Trajectories of depressive symptoms across pregnancy and the extended postpartum period and future cardiovascular health.medRxiv : the preprint server for health sciences · 2026Article
- Patient and Provider Perspectives on Cardiovascular Health Education and Engagement Following Hypertensive Disorders of Pregnancy: A Qualitative Study.BJOG : an international journal of obstetrics and gynaecology · 2026Article
- Persistent and de novo postpartum hypertension: a scoping review of pathophysiology, evaluation, and management.NPJ cardiovascular health · 2026Article
- Stress Trajectory and Hypertension 2 to 7 Years After Delivery: A nuMoM2b-HHS Study.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Cannabis Exposure After Pregnancy and Development of Hypertension in the nuMoM2b Heart Health Study.O&G open · 2026Article
- Risks of cardiometabolic diseases in women with history of adverse pregnancy outcomes.Journal of human hypertension · 2026Review
- Addressing maternal cardiovascular risk: The impact of lactation, adverse pregnancy outcomes, and racial disparities.American heart journal plus : cardiology research and practice · 2025Article
- Myo-inositol to Prevent Pregnancy Complications: Valuable Evidence Amid Complex Etiologies.JAMA · 2025Article
- Higher Levels of Cardiovascular Biomarkers Following Hypertensive Compared to Normotensive Pregnancy.Pregnancy (Hoboken, N.J.) · 2025Article
- Leisure Physical Activity, Sedentary Behavior, and Cardiovascular Health 2-7 yr after Pregnancy in the nuMoM2b Heart Health Study Cohort.Medicine and science in sports and exercise · 2025Article
- Genetic Risk and First-Trimester Cardiovascular Health Predict Hypertensive Disorders of Pregnancy in Nulliparous Women.Journal of the American College of Cardiology · 2025Observational
- Trends in adverse pregnancy outcomes in Louisiana, 2017 to 2022.Scientific reports · 2025Article
24 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors at 18 institutions in 2 countries.
Funding
Abstract
Background Identifying pregnancy-associated risk factors before the development of major cardiovascular disease events could provide opportunities for prevention. The objective of this study was to determine the association between outcomes in first pregnancies and subsequent cardiovascular health. Methods and Results The Nulliparous Pregnancy Outcomes Study Monitoring Mothers-to-be Heart Health Study is a prospective observational cohort that followed 4484 women 2 to 7 years (mean 3.2 years) after their first pregnancy. Adverse pregnancy outcomes (defined as hypertensive disorders of pregnancy, small-for-gestational-age birth, preterm birth, and stillbirth) were identified prospectively in 1017 of the women (22.7%) during this pregnancy. The primary outcome was incident hypertension (HTN). Women without adverse pregnancy outcomes served as controls. Risk ratios (RR) and 95% CIs were adjusted for age, smoking, body mass index, insurance type, and race/ethnicity at enrollment during pregnancy. The overall incidence of HTN was 5.4% (95% CI 4.7% to 6.1%). Women with adverse pregnancy outcomes had higher adjusted risk of HTN at follow-up compared with controls (RR 2.4, 95% CI 1.8-3.1). The association held for individual adverse pregnancy outcomes: any hypertensive disorders of pregnancy (RR 2.7, 95% CI 2.0-3.6), preeclampsia (RR 2.8, 95% CI 2.0-4.0), and preterm birth (RR 2.7, 95% CI 1.9-3.8). Women who had an indicated preterm birth and hypertensive disorders of pregnancy had the highest risk of HTN (RR 4.3, 95% CI 2.7-6.7). Conclusions Several pregnancy complications in the first pregnancy are associated with development of HTN 2 to 7 years later. Preventive care for women should include a detailed pregnancy history to aid in counseling about HTN risk. Clinical Trial Registration URL: http://www.clinicaltrials.gov Unique identifier: NCT02231398.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.