Evidence map›Paper›PMID 31564047›Full record

ArticleInternational ophthalmology2020

A multimodal ophthalmic analysis in patients with systemic sclerosis using ocular response analyzer, corneal topography and specular microscopy.

Huseyin Mayali, Muhammed Altinisik, Secil Sencan, Timur Pirildar, Emin Kurt

Abstract read
PubMed Publisher
In one paragraph

Article in International ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Huseyin MayaliOphthalmology Department, Medical School, Manisa Celal Bayar University, Manisa, Turkey.
Muhammed AltinisikOphthalmology Department, Medical School, Manisa Celal Bayar University, Manisa, Turkey. dr.maltinisik@gmail.com.ORCID http://orcid.org/0000-0003-0239-0180
Secil SencanOphthalmology Department, Tinaztepe Hospital, Izmir, Turkey.
Timur PirildarOphthalmology Department, Medical School, Manisa Celal Bayar University, Manisa, Turkey.
Emin KurtOphthalmology Department, Medical School, Manisa Celal Bayar University, Manisa, Turkey.
Manisa Celal Bayar University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo conduct a multimodal ophthalmic evaluation of systemic sclerosis (SSc) in patients using ocular response analyzer (ORA), Pentacam, and specular microscopy (SM).

methodsThirty-one SSc patients and a group of age- and sex-matched controls were enrolled in this cross-sectional study. Corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPcc), and Goldmann-correlated IOP (IOPg) were measured with ORA. Anterior chamber depth (ACD), central corneal thickness (CCT), and corneal volume (CV) measurements were obtained using Pentacam. Corneal endothelial cell density (ECD) and CCT were evaluated by SM.

resultsSSc patients had significantly lower CH, ACD, and ECD values compared to the control group (p = 0.018; < 0.001; < 0.001, respectively). There was no significant difference regarding CRF, IOP, CV, or CCT measurements acquired by Pentacam and SM. Regarding CCT, SM and Pentacam showed relatively better agreement in SSc patients.

conclusionsMultimodal imaging can provide more comprehensive and useful information regarding the ocular involvement of systemic diseases. The multimodal evaluation in our study demonstrated that the pathologic effects of SSc may manifest as reductions in ACD, corneal elasticity, and ECD before there are any detectable changes in corneal thickness or IOP.

Indexed as

ForecastingAdultAgedCorneaCorneal DiseasesCorneal TopographyCross-Sectional StudiesElasticityFemaleFollow-Up StudiesHumansIntraocular PressureMaleMiddle AgedMultimodal ImagingScleroderma, SystemicCentral corneal thicknessCorneal topographyEndothelial cell densityOcular Response AnalyzerSpecular microscopySystemic sclerosis

Identifiers

PMID31564047
OpenAlexW2976740282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.