Evidence map›Paper›PMID 31563633›Full record

ArticleEuropean journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V2019

Simulated biological fluid exposure changes nanoceria's surface properties but not its biological response.

Robert A Yokel, Matthew L Hancock, Benjamin Cherian, Alexandra J Brooks, Marsha L Ensor, Hemendra J Vekaria, Patrick G Sullivan, Eric A Grulke

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Solid lipid nanoparticles as carriers forFrontiers in aging neuroscience · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Robert A YokelPharmaceutical Sciences, University of Kentucky, Lexington, KY 40536-0596, United States. Electronic address: ryokel@uky.edu.
Matthew L HancockChemical and Materials Engineering, University of Kentucky, Lexington, KY 40506-0046, United States. Electronic address: matthew.hancock@uky.edu.
Benjamin CherianChemical and Materials Engineering, University of Kentucky, Lexington, KY 40506-0046, United States. Electronic address: cherianb@vcu.edu.
Alexandra J BrooksChemical and Materials Engineering, University of Kentucky, Lexington, KY 40506-0046, United States. Electronic address: alexandra.brooks@uky.edu.
Marsha L EnsorPharmaceutical Sciences, University of Kentucky, Lexington, KY 40536-0596, United States. Electronic address: ml.ensor@uky.edu.
Hemendra J VekariaSpinal Cord & Brain Injury Research Center, University of Kentucky, Lexington, KY 40536-0509, United States; Department of Neuroscience, University of Kentucky, Lexington, KY 40536-0509, United States. Electronic address: hemendravekaria@uky.edu.
Patrick G SullivanSpinal Cord & Brain Injury Research Center, University of Kentucky, Lexington, KY 40536-0509, United States; Department of Neuroscience, University of Kentucky, Lexington, KY 40536-0509, United States. Electronic address: patsullivan@uky.edu.
Eric A GrulkeChemical and Materials Engineering, University of Kentucky, Lexington, KY 40506-0046, United States. Electronic address: eric.grulke@uky.edu.
University of Kentucky · US

Funding

Reconciling Nanoceria's Jekyll and Hyde Reputation Toward Safer NanotherapyR01GM109195 · NIGMS · UNIVERSITY OF KENTUCKY · PI YOKEL, ROBERT ALLEN · 2015 to 2018
$1.3M
NIGMS NIH HHS R01 GM109195
6 · The paper itself

Abstract

Nanoscale cerium dioxide (nanoceria) has industrial applications, capitalizing on its catalytic, abrasive, and energy storage properties. It auto-catalytically cycles between Ce

Indexed as

A549 CellsBody FluidsCaco-2 CellsCell Line, TumorCell SurvivalCeriumHumansMitochondriaNanoparticlesOxidation-ReductionOxidative StressOxygen ConsumptionSurface Propertiesceric oxideCeriumA549 cellsBody fluidsCaco-2 cellsCellular respirationCeriumEngineered nanoparticlesHydrodynamic diameterMicroscopy, electron, transmissionNanoceriaNanoparticle coronaSpectroscopy, Fourier transform infraredThermogravimetric analysisX-ray diffraction

Identifiers

PMID31563633
PMCPMC6910233
OpenAlexW2975478516

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.