Evidence map›Paper›PMID 31563134›Full record

ArticleAmerican journal of perinatology2021

Obesity, Second Stage Duration, and Labor Outcomes in Nulliparous Women.

Antonina I Frolova, Nandini Raghuraman, Molly J Stout, Methodius G Tuuli, George A Macones, Alison G Cahill

Abstract read
In one paragraph

Article in American journal of perinatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Antonina I FrolovaDepartment of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri.ORCID 0000-0002-6491-6910
Nandini RaghuramanDepartment of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri.
Molly J StoutDepartment of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri.
Methodius G TuuliDepartment of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri.
George A MaconesDepartment of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri.
Alison G CahillDepartment of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri.

Funding

Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
PREDICTING FETAL ACIDEMIA WITH INTRAPARTUM ELECTRONIC FETAL HEART RATE MONITORINGR01HD061619 · NICHD · WASHINGTON UNIVERSITY · PI CAHILL, ALISON G, MACONES, GEORGE A · 2010 to 2014
$2.9M
Women's Reproductive Health Research Career Development Program at W.U., St LouisK12HD063086 · NICHD · WASHINGTON UNIVERSITY · PI MACONES, GEORGE A · 2009 to 2013
$2.6M
Oxygen for intrauterine resuscitation: Investigating the role of oxidative stressK23HD098315 · NICHD · WASHINGTON UNIVERSITY · PI RAGHURAMAN, NANDINI · 2020 to 2022
$456k
NICHD NIH HHS K12 HD063086NICHD NIH HHS K23 HD098315NICHD NIH HHS R01 HD061619NIDDK NIH HHS P30 DK056341
6 · The paper itself

Abstract

objectiveThis study aimed to estimate second stage duration and its effects on labor outcomes in obese versus nonobese nulliparous women. STUDY

designThis was a secondary analysis of a cohort of nulliparous women who presented for labor at term and reached complete cervical dilation. Adjusted relative risks (aRR) were used to estimate the association between obesity and second stage characteristics, composite neonatal morbidity, and composite maternal morbidity. Effect modification of prolonged second stage on the association between obesity and morbidity was assessed by including an interaction term in the regression model.

resultsCompared with nonobese, obese women were more likely to have a prolonged second stage (aRR: 1.48, 95% CI: 1.18-1.85 for ≥3 hours; aRR: 1.65, 95% CI: 1.18-2.30 for ≥4 hours). Obesity was associated with a higher rate of second stage cesarean (aRR: 1.78, 95% CI: 1.34-2.34) and cesarean delivery for fetal distress (aRR: 2.67, 95% CI: 1.18-3.58). Obesity was also associated with increased rates of neonatal (aRR: 1.38, 95% CI: 1.05-1.80), but not maternal morbidity (aRR: 1.06, 95% CI: 0.90-1.25). Neonatal morbidity risk was not modified by prolonged second stage.

conclusionObesity is associated with increased risk of neonatal morbidity, which is not modified by prolonged second stage of labor.

Indexed as

Obstetric Labor ComplicationsPregnancy OutcomeAdolescentAdultCesarean SectionFemaleHumansInfant, NewbornLabor Stage, SecondLogistic ModelsObesityParityPregnancyProspective StudiesRisk FactorsYoung Adult

Identifiers

PMID31563134
PMCPMC8081034

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.