Evidence map›Paper›PMID 31562509›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2019

Automated meal detection from continuous glucose monitor data through simulation and explanation.

Min Zheng, Baohua Ni, Samantha Kleinberg

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Data-driven meal events detection using blood glucose response patterns.BMC medical informatics and decision making · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Insulin Delivery Hardware: Pumps and Pens.Diabetes technology & therapeutics · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. A New Meal Absorption Model for Artificial Pancreas Systems.Journal of diabetes science and technology · 2022
    Article
  18. Review
  19. Data-Driven Insights on Behavioral Factors that Affect Diabetes Management.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Min ZhengComputer Science, Stevens Institute of Technology, Hoboken, New Jersey, USA.
Baohua NiElectronic Engineering, Tsinghua University, Beijing, China.
Samantha KleinbergComputer Science, Stevens Institute of Technology, Hoboken, New Jersey, USA.
Stevens Institute of Technology · USTsinghua University · CN

Funding

BIGDATA: Causal Inference in Large-Scale Time Series with Rare and Latent EventsR01LM011826 · NLM · THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY · PI KLEINBERG, SAMANTHA · 2013 to 2024
$3.3M
NLM NIH HHS R01 LM011826
6 · The paper itself

Abstract

backgroundArtificial pancreas systems aim to reduce the burden of type 1 diabetes by automating insulin dosing. These systems link a continuous glucose monitor (CGM) and insulin pump with a control algorithm, but require users to announce meals, without which the system can only react to the rise in blood glucose.

objectiveWe investigate whether CGM data can be used to automatically infer meals in daily life even in the presence of physical activity, which can raise or lower blood glucose. MATERIALS AND

methodsWe propose a novel meal detection algorithm that combines simulations with CGM, insulin pump, and heart rate monitor data. When observed and predicted glucose differ, our algorithm uses simulations to test whether a meal may explain this difference. We evaluated our method on simulated data and real-world data from individuals with type 1 diabetes.

resultsIn simulated data, we detected meals earlier and with higher accuracy than was found in prior work (25.7 minutes, 1.2 g error; compared with 48.3 minutes, 17.2 g error). In real-world data, we discovered a larger number of plausible meals than was found in prior work (30 meals, 76.7% accepted; compared with 33 meals, 39.4% accepted). DISCUSSION: Prior research attempted meal detection from CGM, but had delays and lower accuracy in real data or did not allow for physical activity. Our approach can be used to improve insulin dosing in an artificial pancreas and trigger reminders for missed meal boluses.

conclusionsWe demonstrate that meal information can be robustly inferred from CGM and body-worn sensor data, even in challenging environments of daily life.

Indexed as

AlgorithmsBlood Glucose Self-MonitoringInsulin Infusion SystemsMealsBlood GlucoseDiabetes Mellitus, Type 1HumansInfusion Pumps, ImplantableModels, TheoreticalPancreas, ArtificialBlood Glucoseartificialcontinuous glucose monitoringdiabetes mellitus type 1meal detectionpancreas

Identifiers

PMID31562509
PMCPMC6857509
OpenAlexW2975391816

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.