ArticleEvidence-based dentistry2019
Preventing white spot lesions with fluoride pastes.
Article in Evidence-based dentistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- White Spots: Prevention in Orthodontics-Systematic Review of the Literature.International journal of environmental research and public health · 2023Pooled it
- Amelogenin Peptide-Chitosan Hydrogel for Biomimetic Enamel Regrowth.Frontiers in dental medicine · 2021Article
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Design Randomised controlled trial.Study population Patients undergoing routine orthodontic treatment, aged 12 years and older, were randomly allocated to use either Clinpro 5000, Clinpro Tooth Crème or MI Paste Plus for 4 months.Data Analysis Three-way analysis of variance (ANOVA) was used to analyse the Enamel Decalcification Index (EDI) scores of the maxillary and mandibular arches from the right first premolar to the left first premolar at 0.05 level of significance. Fisher-protected least significant difference intervals were used to compare mean EDI scores. Two operators scored photographs independently and their scores were compared by using the t-test; no statistically significant difference (P ≥.05) was found between the operators. Results of each product were analysed individually and amongst themselves. A multilevel mixed-effects Poisson regression was used to model factors predictive of EDI scores for individual teeth.Results Of the 120 subjects enrolled, 100 (35 using Clinpro 5000, 32 using Clinpro Tooth Crème, and 33 using MI Paste Plus) completed the study. The data lends support for Clinpro 5000 providing superior protection against enamel decalcification when compared to Clinpro Crème, and mixed support when compared to MI Paste Plus.Conclusions The use of Clinpro 5000, Clinpro Tooth Crème, and MI Paste Plus all have a reduction effect on white spot lesions when compared to studies reported previously. They found Clinpro 5000 to have a marginally better effect than the two other test pastes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.