Evidence map›Paper›PMID 31562321›Full record

ArticleNature communications2019

Manipulating energy migration within single lanthanide activator for switchable upconversion emissions towards bidirectional photoactivation.

Qingsong Mei, Akshaya Bansal, Muthu Kumara Gnanasammandhan Jayakumar, Zhiming Zhang, Jing Zhang, Hua Huang, Dejie Yu, Chrishan J A Ramachandra, Derek J Hausenloy, Tuck Wah Soong and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 104 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 4 countries.

Qingsong MeiDepartment of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore, 117583, Singapore.
Akshaya BansalDepartment of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore, 117583, Singapore.
Muthu Kumara Gnanasammandhan JayakumarDepartment of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore, 117583, Singapore.
Zhiming ZhangSchool of Environmental and Chemical Engineering, Shanghai University, 99 Shangda Road, 200444, Shanghai, China.
Jing ZhangSchool of Environmental and Chemical Engineering, Shanghai University, 99 Shangda Road, 200444, Shanghai, China.
Hua HuangDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117456, Singapore.
Dejie YuDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117456, Singapore.
Chrishan J A RamachandraCardiovascular & Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.
Derek J HausenloyCardiovascular & Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.
Tuck Wah SoongDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117456, Singapore.
Yong ZhangDepartment of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore, 117583, Singapore. biezy@nus.edu.sg.ORCID http://orcid.org/0000-0002-1303-0458
National University of Singapore · SGShanghai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reliance on low tissue penetrating UV or visible light limits clinical applicability of phototherapy, necessitating use of deep tissue penetrating near-infrared (NIR) to visible light transducers like upconversion nanoparticles (UCNPs). While typical UCNPs produce multiple simultaneous emissions for unidirectional control of biological processes, programmable control requires orthogonal non-overlapping light emissions. These can be obtained through doping nanocrystals with multiple activator ions. However, this requires tedious synthesis and produces complicated multi-shell nanoparticles with a lack of control over emission profiles due to activator crosstalk. Herein, we explore cross-relaxation (CR), a non-radiative recombination pathway typically perceived as deleterious, to manipulate energy migration within the same lanthanide activator ion (Er

Identifiers

PMID31562321
PMCPMC6764961
OpenAlexW2993346437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.