ArticleThe Journal of biological chemistry2019
Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands.
Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 23 citations in OpenAlex.
- Lipid Composition and Thermotropic Properties of Meibum of Animal Models and Humans with Meibomian Gland Dysfunction.International journal of molecular sciences · 2025Article
- Lipid composition determines thermotropic properties of meibum of animals and humans with Meibomian gland disorders.bioRxiv : the preprint server for biology · 2025Article
- Physiological Effects of Soat1 Inactivation on Homeostasis of the Mouse Ocular Surface.Investigative ophthalmology & visual science · 2024Article
- LRG1 and SDR16C5 protein expressions differ according to HPV status in oropharyngeal squamous cell carcinoma.Scientific reports · 2024Article
- Epidermal retinol dehydrogenases cyclically regulate stem cell markers and clock genes and influence hair composition.Communications biology · 2024Article
- Characterization of Transcriptomic and Proteomic Changes in the Skin after Chronic Fluocinolone Acetonide Treatment.Biomolecules · 2022Article
- Vitamin A in Skin and Hair: An Update.Nutrients · 2022Review
- Mechanisms of Feedback Regulation of Vitamin A Metabolism.Nutrients · 2022Review
- Separation and purification of plant terpenoids from biotransformation.Engineering in life sciences · 2021Review
- Estrogen regulates the expression of retinoic acid synthesis enzymes and binding proteins in mouse skin.Nutrition research (New York, N.Y.) · 2021Article
- Reorganization of Metabolism during Cardiomyogenesis Implies Time-Specific Signaling Pathway Regulation.International journal of molecular sciences · 2021Article
- Dietary Vitamin A Impacts Refractory Telogen.Frontiers in cell and developmental biology · 2021Article
- Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes.Journal of developmental biology · 2020Review
- Post-natal all-trans-retinoic acid biosynthesis.Methods in enzymology · 2020Article
- Generation of Retinaldehyde for Retinoic Acid Biosynthesis.Biomolecules · 2019Review
- Meibomian gland development: Where, when and how?Differentiation; research in biological diversityReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
Retinol dehydrogenases catalyze the rate-limiting step in the biosynthesis of retinoic acid, a bioactive lipid molecule that regulates the expression of hundreds of genes by binding to nuclear transcription factors, the retinoic acid receptors. Several enzymes exhibit retinol dehydrogenase activities
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.