Evidence map›Paper›PMID 31562212›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2019

STAT4 Directs a Protective Innate Lymphoid Cell Response to Gastrointestinal Infection.

Sarah J Dulson, Emily E Watkins, David K Crossman, Laurie E Harrington

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Divergent roles for STAT4 in shaping differentiation of cytotoxic ILC1 and NK cells during gut inflammation.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Transcriptional control of ILC identity.Frontiers in immunology · 2023
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Innate Lymphoid Cells in Response to Intracellular Pathogens: ProtectionFrontiers in cellular and infection microbiology · 2021
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sarah J DulsonDepartment of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294.ORCID 0000-0002-1965-0543
Emily E WatkinsDepartment of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294.
David K CrossmanDepartment of Genetics, University of Alabama at Birmingham, Birmingham, AL 35294; and.ORCID 0000-0002-0981-169X
Laurie E HarringtonDepartment of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294; lharring@uab.edu.ORCID 0000-0002-6832-9529
University of Alabama at Birmingham · US

Funding

SEEDING POSTDOCTORAL INNOVATORS IN RESEARCH &EDUCATIONK12GM000678 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DONALD T LYSLE, Kathryn Joanna Reissner · 1999 to 2026
$30.9M
IMMUNOLOGIC DISEASES AND BASIC IMMUNOLOGYT32AI007051 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Laurie Ellen Harrington · 1985 to 2026
$13.1M
ROS Modulation of Innate and Adaptive Immunity in RAP30AR048311 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MOUNTZ, JOHN D · 2001 to 2017
$9.5M
STAT4 regulation of effector CD4 T cells and CNS inflammationR01AI113007 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HARRINGTON, LAURIE ELLEN · 2015 to 2019
$1.8M
Sialylation dependent control of CD8 T cell stemness during chronic viral infectionR21AI142641 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HARRINGTON, LAURIE ELLEN · 2019 to 2020
$408k
NIAID NIH HHS R01 AI113007NIAID NIH HHS R21 AI142641NIAID NIH HHS T32 AI007051NIAMS NIH HHS P30 AR048311NIGMS NIH HHS K12 GM000678
6 · The paper itself

Abstract

Innate lymphoid cells (ILCs) are strategically positioned at mucosal barrier surfaces where they respond quickly to infection or injury. Therefore, we hypothesized that ILCs are key contributors to the early immune response in the intestine against

Indexed as

AnimalsGastrointestinal DiseasesHomeodomain ProteinsImmunity, InnateInterferon-gammaListeriosisLymphocyte ActivationLymphocytesMiceMice, Inbred C57BLSignal TransductionSTAT4 Transcription FactorHomeodomain ProteinsInterferon-gammaRAG-1 proteinStat4 protein, mouseSTAT4 Transcription Factor

Identifiers

PMID31562212
PMCPMC6810903
OpenAlexW2976202438

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.