Evidence map›Paper›PMID 31562189›Full record

ArticleJournal of cell science2019

Discovery of aspirin-triggered eicosanoid-like mediators in a

Silvio Panettieri, Indira Paddibhatla, Jennifer Chou, Roma Rajwani, Rebecca S Moore, Tamara Goncharuk, George John, Shubha Govind

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  5. iScience · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Insects · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Silvio PanettieriDepartment of Chemistry & Biochemistry, The City College of New York, New York, NY 10031, USA.ORCID 0000-0001-6736-0455
Indira PaddibhatlaPhD Program in Biology, Graduate Center, City University of New York, 365 Fifth Avenue, New York, NY 10016, USA.ORCID 0000-0002-3057-2160
Jennifer ChouBiology Department, The City College of New York, 160 Convent Avenue, New York, NY 10031, USA.ORCID 0000-0003-3351-5855
Roma RajwaniBiology Department, The City College of New York, 160 Convent Avenue, New York, NY 10031, USA.ORCID 0000-0002-3729-8213
Rebecca S MooreBiology Department, The City College of New York, 160 Convent Avenue, New York, NY 10031, USA.ORCID 0000-0003-3155-3436
Tamara GoncharukBiology Department, The City College of New York, 160 Convent Avenue, New York, NY 10031, USA.ORCID 0000-0002-5747-7227
George JohnDepartment of Chemistry & Biochemistry, The City College of New York, New York, NY 10031, USA sgovind@ccny.cuny.edu gjohn@ccny.cuny.edu.ORCID 0000-0002-0382-1256
Shubha GovindBiology Department, The City College of New York, 160 Convent Avenue, New York, NY 10031, USA sgovind@ccny.cuny.edu gjohn@ccny.cuny.edu.ORCID 0000-0002-6436-639X
City College of New York · USThe Graduate Center, CUNY · US

Funding

VOLTAGE GATING OF ION CHANNELS--SIMULATIONS AND AB INITIO CALCULATIONSS06GM008168 · NIGMS · CITY COLLEGE OF NEW YORK · PI HUBBARD, KAREN · 1989 to 2010
$17.6M
Cellular/Molecular Basis of Development: Research CenterG12MD007603 · NIMHD · CITY COLLEGE OF NEW YORK · PI PEZZANO, MARK · 2012 to 2017
$11.5M
NIGMS NIH HHS S06 GM008168NIMHD NIH HHS G12 MD007603
6 · The paper itself

Abstract

Epidemiologic studies have linked the use of aspirin to a decline in chronic inflammation that underlies many human diseases, including some cancers. Aspirin reduces the levels of cyclooxygenase-mediated pro-inflammatory prostaglandins, promotes the production of pro-resolution molecules, and triggers the production of anti-inflammatory electrophilic mono-oxygenated (EFOX) lipid mediators. We investigated the effects of aspirin in fruit fly models of chronic inflammation. Ectopic Toll/NF-κB and JAK/STAT signaling in mutant

Indexed as

AnimalsAspirinDrosophila melanogasterDrosophila ProteinsEicosanoidsFemaleHematopoietic Stem CellsInflammationInflammation MediatorsJanus KinasesMacrophagesMaleNF-kappa BPhylogenySignal TransductionTranscription FactorsAspirinDrosophila ProteinsEicosanoidshop protein, DrosophilaInflammation MediatorsJanus KinasesNF-kappa BTranscription Factors13-HODE13-oxoODEAspirinDrosophilaEFOXEicosanoidFatty acidMacrophagesNF-κBResolutionSystemic inflammation

Identifiers

PMID31562189
PMCPMC7033724
OpenAlexW2976077572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.