Evidence map›Paper›PMID 31562169›Full record

ArticleApplied and environmental microbiology2019

Heterologous Expression of a Cryptic Gene Cluster from Streptomyces leeuwenhoekii C34

Juan Pablo Gomez-Escribano, Jean Franco Castro, Valeria Razmilic, Scott A Jarmusch, Gerhard Saalbach, Rainer Ebel, Marcel Jaspars, Barbara Andrews, Juan A Asenjo, Mervyn J Bibb

Open access · hybridAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. Lasso peptides: A focus on therapeutic index.World journal of microbiology & biotechnology · 2025
    Review
  4. Frontiers in bioinformatics · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Bacterial natural product discovery by heterologous expression.Journal of industrial microbiology & biotechnology · 2023
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. How to harness biosynthetic gene clusters of lasso peptides.Journal of industrial microbiology & biotechnology · 2020
    Review
  17. Lasso Peptides: Heterologous Production and Potential Medical Application.Frontiers in bioengineering and biotechnology · 2020
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Juan Pablo Gomez-EscribanoDepartment of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom.
Jean Franco Castro *Department of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom.
Valeria Razmilic *Department of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom.
Scott A Jarmusch *Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Old Aberdeen, United Kingdom.
Gerhard SaalbachDepartment of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom.
Rainer EbelMarine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Old Aberdeen, United Kingdom.
Marcel JasparsMarine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Old Aberdeen, United Kingdom.
Barbara AndrewsCentre for Biotechnology and Bioengineering (CeBiB), Department of Chemical Engineering and Biotechnology, Universidad de Chile, Santiago, Chile.
Juan A AsenjoCentre for Biotechnology and Bioengineering (CeBiB), Department of Chemical Engineering and Biotechnology, Universidad de Chile, Santiago, Chile.
Mervyn J BibbDepartment of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom mervyn.bibb@jic.ac.uk.
John Innes Centre · GBUniversity of Aberdeen · GBUniversity of Chile · CL

Funding

Biotechnology and Biological Sciences Research Council BB/J004561/1
6 · The paper itself

Abstract

Analysis of the genome sequence of

Indexed as

Gene ExpressionMultigene FamilyBacterial ProteinsPeptidesStreptomycesBacterial ProteinsPeptidesheterologous expressionlasso peptidenatural productsRiPPStreptomyces

Identifiers

PMID31562169
PMCPMC6856326
OpenAlexW2975615186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.