Evidence map›Paper›PMID 31561640›Full record

ArticlePharmaceutics2019

Comparison of Traditional and Ultrasound-Enhanced Electrospinning in Fabricating Nanofibrous Drug Delivery Systems.

Enni Hakkarainen, Arle Kõrkjas, Ivo Laidmäe, Andres Lust, Kristian Semjonov, Karin Kogermann, Heikki J Nieminen, Ari Salmi, Ossi Korhonen, Edward Haeggström and 1 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Enni HakkarainenSchool of Pharmacy, University of Eastern Finland, 70210 Kuopio, Finland. hakkarainen.enni@gmail.com.
Arle KõrkjasInstitute of Pharmacy, Faculty of Medicine, University of Tartu, 50411 Tartu, Estonia. arle.korkjas@ut.ee.
Ivo LaidmäeInstitute of Pharmacy, Faculty of Medicine, University of Tartu, 50411 Tartu, Estonia. ivo.laidmae@ut.ee.
Andres LustInstitute of Pharmacy, Faculty of Medicine, University of Tartu, 50411 Tartu, Estonia. andres.lust@ut.ee.
Kristian SemjonovInstitute of Pharmacy, Faculty of Medicine, University of Tartu, 50411 Tartu, Estonia. kristian.semjonov@gmail.com.
Karin KogermannInstitute of Pharmacy, Faculty of Medicine, University of Tartu, 50411 Tartu, Estonia. kkogermann@gmail.com.
Heikki J NieminenElectronics Research Laboratory, Department of Physics, University of Helsinki, 00014 Helsinki, Finland. heikki.j.nieminen@aalto.fi.
Ari SalmiElectronics Research Laboratory, Department of Physics, University of Helsinki, 00014 Helsinki, Finland. ari.salmi@helsinki.fi.
Ossi KorhonenSchool of Pharmacy, University of Eastern Finland, 70210 Kuopio, Finland. ossi.korhonen@uef.fi.
Edward HaeggströmElectronics Research Laboratory, Department of Physics, University of Helsinki, 00014 Helsinki, Finland. edward.haeggstrom@helsinki.fi.
Jyrki HeinämäkiInstitute of Pharmacy, Faculty of Medicine, University of Tartu, 50411 Tartu, Estonia. jyrki.heinamaki@ut.ee.

Funding

Eesti Teadusagentuur IUT34-18Eesti Teadusagentuur PUT1088
6 · The paper itself

Abstract

We investigated nozzleless ultrasound-enhanced electrospinning (USES) as means to generate nanofibrous drug delivery systems (DDSs) for pharmaceutical and biomedical applications. Traditional electrospinning (TES) equipped with a conventional spinneret was used as a reference method. High-molecular polyethylene oxide (PEO) and chitosan were used as carrier polymers and theophylline anhydrate as a water-soluble model drug. The nanofibers were electrospun with the diluted mixture (7:3) of aqueous acetic acid (90%

Indexed as

nanotechnology, nanofibers, traditional electrospinning, ultrasound-enhanced electrospinning, drug delivery system

Identifiers

PMID31561640
PMCPMC6835569

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.