Evidence map›Paper›PMID 31561511›Full record

ArticleInternational journal of molecular sciences2019

The Organogermanium Compound THGP Suppresses Melanin Synthesis via Complex Formation with L-DOPA on Mushroom Tyrosinase and in B16 4A5 Melanoma Cells.

Junya Azumi, Tomoya Takeda, Yasuhiro Shimada, Hisashi Aso, Takashi Nakamura

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Journal of the American Chemical Society · 2023
    Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Junya AzumiAsai Germanium Research Institute Co., Ltd. Suzuranoka 3-131, Hakodate, Hokkaido 042-0958, Japan. j.azumi@asai-ge.co.jp.ORCID 0000-0003-2902-1561
Tomoya TakedaAsai Germanium Research Institute Co., Ltd. Suzuranoka 3-131, Hakodate, Hokkaido 042-0958, Japan. tomo.t621@asai-ge.co.jp.
Yasuhiro ShimadaAsai Germanium Research Institute Co., Ltd. Suzuranoka 3-131, Hakodate, Hokkaido 042-0958, Japan. y.shimada@asai-ge.co.jp.
Hisashi AsoCellular Biology Laboratory, Graduate School of Agricultural Science, Tohoku University, Miyagi, Sendai 980-8572, Japan. asosan@tohoku.ac.jp.
Takashi NakamuraAsai Germanium Research Institute Co., Ltd. Suzuranoka 3-131, Hakodate, Hokkaido 042-0958, Japan. nakamura@asai-ge.co.jp.
Asai Germanium Research Institute · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The organogermanium compound 3-(trihydroxygermyl)propanoic acid (THGP) has various biological activities. We previously reported that THGP forms a complex with

Indexed as

AgaricalesAnimalsBiosynthetic PathwaysLevodopaMelaninsMelanoma, ExperimentalMiceMonophenol MonooxygenaseOrganometallic Compounds3-(trihydroxygermyl)propanoic acidLevodopaMelaninsMonophenol MonooxygenaseOrganometallic CompoundsmelanogenesisorganogermaniumTHGP

Identifiers

PMID31561511
PMCPMC6801725
OpenAlexW2975279073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.