Evidence map›Paper›PMID 31561507›Full record

ArticleCancers2019

Personalizing the Prediction of Colorectal Cancer Prognosis by Incorporating Comorbidities and Functional Status into Prognostic Nomograms.

Daniel Boakye, Lina Jansen, Martin Schneider, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner

Abstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel BoakyeDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. d.boakye@dkfz.de.ORCID 0000-0003-4684-0841
Lina JansenDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. l.jansen@dkfz.de.
Martin SchneiderDepartment of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, 69120 Heidelberg, Germany. m.schneider@uni-heidelberg.de.
Jenny Chang-ClaudeUnit of Genetic Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. j.chang-claude@dkfz.de.
Michael HoffmeisterDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. m.hoffmeister@dkfz.de.
Hermann BrennerDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. h.brenner@dkfz.de.

Funding

Deutsche Forschungsgemeinschaft BR 1704/6-1, BR 1704/6-3, BR 1704/6-4, CH 117/1-1German Federal Ministry of Education and Research 01KH0404, 01ER0814, 01ER0815, 01ER1505A, 01ER1505BMinistry of Science, Research and Arts of Baden-Wuerttemberg None
6 · The paper itself

Abstract

Despite consistent evidence that comorbidities and functional status (FS) are strong prognostic factors for colorectal cancer (CRC) patients, these important characteristics are not considered in prognostic nomograms. We assessed to what extent incorporating these characteristics into prognostic models enhances prediction of CRC prognosis. CRC patients diagnosed in 2003-2014 who were recruited into a population-based study in Germany and followed over a median time of 4.7 years were randomized into training (

Indexed as

colorectal neoplasmcomorbidityfunctional statusnomogrampersonalized medicineprognosis

Identifiers

PMID31561507
PMCPMC6826360

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.