Evidence map›Paper›PMID 31561479›Full record

ReviewMolecules (Basel, Switzerland)2019

Macromolecular Nanocrystal Structural Analysis with Electron and X-Rays: A Comparative Review.

Krishna P Khakurel, Borislav Angelov, Jakob Andreasson

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Structure of L-arginine and detection of trace DL-arginine by 3D ED.Acta crystallographica. Section C, Structural chemistry · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Design and fabrication of 3D-printedJournal of applied crystallography · 2024
    Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Krishna P KhakurelInstitute of Physics, ELI Beamlines, Academy of Sciences of the Czech Republic, Na Slovance 2, CZ-18221 Prague, Czech Republic. Krishna.Khakurel@eli-beams.eu.
Borislav AngelovInstitute of Physics, ELI Beamlines, Academy of Sciences of the Czech Republic, Na Slovance 2, CZ-18221 Prague, Czech Republic. Borislav.Angelov@eli-beams.eu.
Jakob AndreassonInstitute of Physics, ELI Beamlines, Academy of Sciences of the Czech Republic, Na Slovance 2, CZ-18221 Prague, Czech Republic. Jakob.Andreasson@eli-beams.eu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crystallography has long been the unrivaled method that can provide the atomistic structural models of macromolecules, using either X-rays or electrons as probes. The methodology has gone through several revolutionary periods, driven by the development of new sources, detectors, and other instrumentation. Novel sources of both X-ray and electrons are constantly emerging. The increase in brightness of these sources, complemented by the advanced detection techniques, has relaxed the traditionally strict need for large, high quality, crystals. Recent reports suggest high-quality diffraction datasets from crystals as small as a few hundreds of nanometers can be routinely obtained. This has resulted in the genesis of a new field of macromolecular nanocrystal crystallography. Here we will make a brief comparative review of this growing field focusing on the use of X-rays and electrons sources.

Indexed as

ElectronsModels, MolecularX-RaysCrystallography, X-RayMacromolecular SubstancesMolecular StructureNanoparticlesMacromolecular Substanceselectron diffractionnanocrystallographyX-ray free-electron laser

Identifiers

PMID31561479
PMCPMC6804143

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.