Evidence map›Paper›PMID 31561443›Full record

ArticleBiosensors2019

Influence of Graphene Oxide Concentration when Fabricating an Electrochemical Biosensor for DNA Detection.

Elena A Chiticaru, Luisa Pilan, Celina-Maria Damian, Eugeniu Vasile, Jorge S Burns, Mariana Ioniţă

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Elena A ChiticaruFaculty of Medical Engineering, University Politehnica of Bucharest, Gh Polizu 1-7, 011061 Bucharest, Romania.
Luisa PilanDepartment of Inorganic Chemistry, Physical Chemistry and Electrochemistry, University Politehnica of Bucharest, 1-7, Polizu St., 011061 Bucharest, Romania. luisa_pilan@yahoo.com.ORCID 0000-0001-5543-2888
Celina-Maria DamianAdvanced Polymer Materials Group, University Politehnica of Bucharest, Gh Polizu 1-7, 011061 Bucharest, Romania.
Eugeniu VasileFaculty of Applied Chemistry and Material Science, University Politehnica of Bucharest, 1-7 Gh. Polizu, 011061 Bucharest, Romania.
Jorge S BurnsFaculty of Medical Engineering, University Politehnica of Bucharest, Gh Polizu 1-7, 011061 Bucharest, Romania.
Mariana IoniţăFaculty of Medical Engineering, University Politehnica of Bucharest, Gh Polizu 1-7, 011061 Bucharest, Romania. mariana.ionita@polimi.it.
Universitatea Națională de Știință și Tehnologie Politehnica București · ROUniversity of Modena and Reggio Emilia · IT

Funding

European Regional Development Fund 154/25.11.2016, P_37_221/2015
6 · The paper itself

Abstract

We have investigated the influence exerted by the concentration of graphene oxide (GO) dispersion as a modifier for screen printed carbon electrodes (SPCEs) on the fabrication of an electrochemical biosensor to detect DNA hybridization. A new pretreatment protocol for SPCEs, involving two successive steps in order to achieve a reproducible deposition of GO, is also proposed. Aqueous GO dispersions of different concentrations (0.05, 0.1, 0.15, and 0.2 mg/mL) were first drop-cast on the SPCE substrates and then electrochemically reduced. The electrochemical properties of the modified electrodes were investigated after each modification step by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS), while physicochemical characterization was performed by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and Raman spectroscopy. Finally, the sensing platform was obtained by the simple adsorption of the single-stranded DNA probe onto the electrochemically reduced GO (RGO)-modified SPCEs under optimized conditions. The hybridization was achieved by incubating the functionalized SPCEs with complementary DNA target and detected by measuring the change in the electrochemical response of [Fe(CN)

Indexed as

Biosensing TechniquesNucleic Acid HybridizationDNADNA ProbesElectrochemical TechniquesElectrodesGraphiteMicroscopy, Electron, ScanningPhotoelectron SpectroscopySpectrum Analysis, RamanDNADNA Probesgraphene oxideGraphiteDNA adsorptionelectrochemical biosensorreduced graphene oxidescreen printed carbon electrodes

Identifiers

PMID31561443
PMCPMC6955971
OpenAlexW2975623157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.