ReviewAnimals : an open access journal from MDPI2019
Mammary Defences and Immunity against Mastitis in Sheep.
Review in Animals : an open access journal from MDPI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 49 citations in OpenAlex.
- Th1 and Th2 Cytokine Profiles in Ewes with Subclinical Mastitis Caused byVeterinary sciences · 2026Article
- Periparturient coenzyme Q10 administration: effects on immunity, milk quality, and growth performance in sheep.Tropical animal health and production · 2026Article
- Baicalin alleviates mastitis in dairy cows by targeting IL-17RA to inhibit IL-17 signaling pathway activation.Journal of animal science and biotechnology · 2026Article
- Soy Protein Isolate-Stachyose Emulsion Gel for the Delivery of Vitamin DAnimals : an open access journal from MDPI · 2025Article
- Evaluating gene expression and biomarkers for mastitis resistance in Barki sheep.Scientific reports · 2025Article
- Transcriptomics-Based Study of Immune Genes Associated with Subclinical Mastitis in Bactrian Camels.Veterinary sciences · 2025Article
- Using infrared thermography to determine changes in teat skin surface temperature after machine milking in dairy cows.JDS communications · 2024Article
- Evaluation of ARFI elastography for detecting active mastitis in sheep with previous fibrous lesions: a study of mammary parenchyma and supramammary lymph nodes.Animal reproduction · 2024Article
- Punch-excised explants of bovine mammary gland to model early immune response to infection.Journal of animal science and biotechnology · 2023Article
- Unique Peptides of Cathelicidin-1 in the Early Detection of Mastitis-In Silico Analysis.International journal of molecular sciences · 2023Article
- Clinicopathological study on camel mastitis at Matrouh Governorate.Journal of advanced veterinary and animal research · 2023Article
- Immunological and Oxidative Biomarkers in Bovine Serum from Healthy, Clinical, and Sub-Clinical Mastitis Caused byAnimals : an open access journal from MDPI · 2023Article
- Vaccination against Bacterial Mastitis in Sheep.Vaccines · 2022Article
- The JMJD3 histone demethylase inhibitor GSK-J1 ameliorates lipopolysaccharide-induced inflammation in a mastitis model.The Journal of biological chemistry · 2022Article
- Jaagsiekte sheep retrovirus found in milk macrophages but not in milk lymphocytes or mammary gland epithelia of naturally infected sheep.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022Article
- A live yeast supplementation to gestating ewes improves bioactive molecule composition in colostrum with no impact on its bacterial composition and beneficially affects immune status of the offspring.Journal of nutritional science · 2022Article
- Mortality of Dairy Sheep during the Peri-Parturient Period: Results of a Field Investigation in Greece.Animals : an open access journal from MDPI · 2021Article
- Polymorphism of Selected Regions ofAnimals : an open access journal from MDPI · 2020Article
- Size of supernumerary teats in sheep correlates with complexity of the anatomy and microenvironment.Journal of anatomy · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objectives of this review paper are to present udder defences, including teat of the udder, mammary epithelial cells, leucocytes, immunoglobulins, complement system and chemical antibacterial agents, to describe cooperation and interactions between them and to elaborate on potentials regarding their significance in mammary immunisation strategies. The teat of the udder provides initial protection to the mammary gland. The mammary epithelial cells synthesise antibacterial proteins and the leucocytes produce various inflammation mediators (cytokines or chemokines), phagocytose bacteria and recognise antigenic structures. In the mammary gland, four immunoglobulins (IgG1, IgG2, IgM and IgA) have important roles against bacterial pathogens. The complement system is a collection of proteins, participating in the inflammatory process through various pathways. Other components contributing to humoral mammary defence include lactoferrin, lysozyme and the lactoperoxidase/myeloperoxidase systems, as well as oligosaccharides, gangliosides, reactive oxygen species, acute phase proteins (e.g., haptoglobin and serum amyloid A), ribonucleases and a wide range of antimicrobial peptides. Management practices, genetic variations and nutrition can influence mammary defences and should be taken into account in the formulation of prevention strategies against ovine mastitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.