ArticleJournal of Parkinson's disease2020
Speeding Up Gait in Parkinson's Disease.
Article in Journal of Parkinson's disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Gait and Balance Assessments using Smartphone Applications in Parkinson's Disease: A Systematic Review.Journal of medical systems · 2021Pooled it
- Pooled it
- Effects of motor and cognitive complex training on obstacle walking and brain activity in people with Parkinson's disease: a randomized controlled trial.European journal of physical and rehabilitation medicine · 2024Trial
- Vertical locomotion improves horizontal locomotion: effects of climbing on gait and other mobility aspects in Parkinson's disease. A secondary analysis from a randomized controlled trial.Journal of neuroengineering and rehabilitation · 2024Trial
- An 8-week aerobic cycling intervention elicits improved gait velocity and biomechanics in persons with Parkinson's disease.Gait & posture · 2022Trial
- Measuring Walking Stability with a Mobile Phone in Older Adults: A Validation Study.Sensors (Basel, Switzerland) · 2026Article
- Gait dysfunction as an early marker of phenoconversion in REM sleep behavior disorder.Scientific reports · 2026Article
- Walking Speed Explains Apparent Ground Reaction Force Differences in Parkinson's Disease: A Waveform-Level SPM Analysis During Normal and Virtual Reality Walking.Parkinson's disease · 2026Article
- Modeling and optimizing deep brain stimulation to enhance gait in Parkinson's disease: personalized treatment with neurophysiological insights.NPJ Parkinson's disease · 2025Article
- Influence of strength and power training on the rate of force development, peak force and functional mobility in elderly people with Parkinson's disease: a randomized controlled trial.Frontiers in neurology · 2025Article
- Adjustability of Gait Speed in Clinics and Free-Living Environments for People With Parkinson's Disease.Journal of movement disorders · 2024Article
- A Review of Recent Advances in Cognitive-Motor Dual-Tasking for Parkinson's Disease Rehabilitation.Sensors (Basel, Switzerland) · 2024Review
- Early-onset and late-onset Parkinson's disease exhibit a different profile of gait and posture features based on the Kinect.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Gait physiotherapy with motor imagery in people with Parkinson's disease: a protocol for randomized control GAITimagery trial.Frontiers in neurology · 2024Article
- Multiscale Entropy Algorithms to Analyze Complexity and Variability of Trunk Accelerations Time Series in Subjects with Parkinson's Disease.Sensors (Basel, Switzerland) · 2023Article
- Gait speed and individual characteristics are related to specific gait metrics in neurotypical adults.Scientific reports · 2023Article
- Reduced Range of Gait Speed: A Parkinson's Disease-Specific Symptom?Journal of Parkinson's disease · 2023Article
- Digital gait markers to potentially distinguish fragile X-associated tremor/ataxia syndrome, Parkinson's disease, and essential tremor.Frontiers in neurology · 2023Article
- Machine Learning Approach to Support the Detection of Parkinson's Disease in IMU-Based Gait Analysis.Sensors (Basel, Switzerland) · 2022Article
- The Efficacy of a Newly Developed Cueing Device for Gait Mobility in Parkinson's Disease.Parkinson's disease · 2022Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundGait speed is an important outcome that relates to mobility, function, and mortality, and is altered in people with Parkinson's disease (PwPD). However, changes in gait speed may not reflect changes in other important aspects of gait.
objectiveTo characterize which outcomes change concomitantly with walking speed in PwPD. This information can inform the choice of outcome variables for characterizing and tracking gait performance in this population.
methods67 PwPD and 40 neurotypical adults completed 2-minute overground walking bouts at comfortable and fast self-selected speeds. Eight inertial sensors were used to characterize gait and turning. We identified a subset of participants (38 per group) where the PD participant's "fast" walk was similar speed to neurotypical participants "comfortable" walk, facilitating an across-group gait comparison controlling for gait speed.
resultsWalking at fast gait speed compared to comfortable lead to significant changes in stride length, cadence, and stride time variability, but not in steps to turn, trunk ROM, and trunk and lumbar stability in PwPD. Sub-group analyses showed that despite walking at a similar speed as neurotypical adults, PwPD exhibit altered turning outcomes, lumbar stability, and stride length/cadence.
conclusionsGait speed is a critical outcome for characterizing mobility. However, in PwPD, several important outcomes do not exhibit a uniform relationship with gait speed, and remain altered compared to neurotypical adults despite "normalizing" walking speed. Given the complex relationship between gait speed and other gait quality measures, care should be taken when choosing outcome measures to characterize the breadth of gait abnormality in PwPD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.