Evidence map›Paper›PMID 31560884›Full record

ReviewFrontiers in neuroendocrinology2019

Lifelong consequences of brain injuries during development: From risk to resilience.

Zachary M Weil, Kate Karelina

Abstract readReview
In one paragraph

Review in Frontiers in neuroendocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zachary M WeilDepartment of Neuroscience, Group in Behavioral Neuroendocrinology, Center for Brain and Spinal Cord Repair, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. Electronic address: Zachary.weil@hsc.wvu.edu.
Kate KarelinaDepartment of Neuroscience, Group in Behavioral Neuroendocrinology, Center for Brain and Spinal Cord Repair, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
The Ohio State University Wexner Medical Center · US

Funding

Neuroendocrine Determinants of Sex Differences in Post-traumatic Alcohol Self AdministrationR21AA026356 · NIAAA · WEST VIRGINIA UNIVERSITY · PI WEIL, ZACHARY MARC · 2018 to 2019
$410k
NIAAA NIH HHS R21 AA026356
6 · The paper itself

Abstract

Traumatic brain injuries in children represent a major public health issue and even relatively mild injuries can have lifelong consequences. However, the outcomes from these injuries are highly heterogeneous, with most individuals recovering fully, but a substantial subset experiencing prolonged or permanent disabilities across a number of domains. Moreover, brain injuries predispose individuals to other kinds of neuropsychiatric and somatic illnesses. Critically, the severity of the injury only partially predicts subsequent outcomes, thus other factors must be involved. In this review, we discuss the psychological, social, neuroendocrine, and autonomic processes that are disrupted following traumatic brain injury during development, and consider the mechanisms the mediate risk or resilience after traumatic brain injury in this vulnerable population.

Indexed as

Autonomic Nervous SystemBehavioral SymptomsBrain Injuries, TraumaticHuman DevelopmentHypothalamo-Hypophyseal SystemNeurosecretory SystemsSocial Behavior DisordersStress Disorders, Post-TraumaticGrowth HormoneHumansGrowth HormoneAutonomicHPA axisPituitary dysfunctionResilienceRiskStressTraumatic brain injury

Identifiers

PMID31560884
PMCPMC6905510
OpenAlexW2976737238

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.