ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2020
Risk factors for death and amputation in acute leg compartment syndrome.
Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Post-fasciotomy complications in lower extremity acute compartment syndrome: a systematic review and proportional meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Pooled it
- Independent Predictors of Major Limb Amputation: A Systematic Review and Meta-Analysis of Adjusted Risk Factors.Healthcare (Basel, Switzerland) · 2026Review
- Clinical phenotypes and risk stratification for limb-threatening outcomes in acute compartment syndrome: a multicenter externally validated study.Frontiers in artificial intelligence · 2026Article
- A Multi-institutional Assessment of Causes, Reoperation Rates, and Mortality in Forearm Acute Compartment Syndrome.Plastic and reconstructive surgery. Global open · 2025Article
- A nomogram for predicting ischaemic muscle sequelae after revascularization in patients with traumatic femoral-popliteal artery injuries: a retrospective cohort study.International orthopaedics · 2025Article
- The effects of timing on fasciotomy outcomes in compartment syndrome - experience from crush-induced trauma following 2023 Turkey earthquakes.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- Risk factors for amputation in opioid-related compartment syndrome.Archives of orthopaedic and trauma surgery · 2024Article
- Fasciotomy and rate of amputation after tibial fracture in adults: a population-based cohort study.OTA international : the open access journal of orthopaedic trauma · 2024Article
- Risk factors for poor outcomes in patients with acute lower leg compartment syndrome: a retrospective study of 103 cases.Journal of orthopaedic surgery and research · 2024Article
- Article
- Comparison of intracompartment pressure changes in tibial plateau fractures and controlled people: A pilot study.PloS one · 2024Article
- Surgical Demographics of Acute Hand Compartment Syndrome.Hand (New York, N.Y.) · 2023Review
- Characteristics and outcomes of patients who undergo fasciotomies for upper arm compartment syndrome.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Article
- Acute compartment syndrome of the leg caused by cocaine use, creatine supplementation and vigorous exercise.Journal of surgical case reports · 2022Article
- A Rare Case of Acute Compartment Syndrome (ACS) Involving the Upper Limb in a Patient on Warfarin.Cureus · 2022Article
- Developing an in-vivo physiological porcine model of inducing acute atraumatic compartment syndrome towards a non-invasive diagnosis using shear wave elastography.Scientific reports · 2021Article
- Association of trauma severity scores with limb amputation and death in acute leg compartment syndrome.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2021Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe primary objective of this study is to determine whether time from injury to fasciotomy is associated with increased risk for death or limb amputation in patients with acute leg compartment syndrome. The secondary objective of this study is to identify other risk factors for death or limb amputation in patients with acute leg compartment syndrome.
methodsIn an institutional review board approved retrospective study, we identified 546 patients with acute compartment syndrome of 558 legs treated with fasciotomies from January 2000 to June 2015 at two Level I trauma centers. Our primary outcome measures were death and limb amputation during inpatient hospital admission. Electronic medical records were analyzed for patient-related factors and treatment-related factors. Bivariate analyses were used to screen for variables associated with our primary outcome measures, and explanatory variables with a p value below 0.05 were included in our multivariable logistic regression analyses.
resultsIn-hospital death occurred in 6.6% and in-hospital limb amputation occurred in 9.5% of acute leg compartment syndrome patients. Neither death nor limb amputation was found to be associated with time from injury to fasciotomy. Multivariable logistic regression analyses showed that older age (p = 0.03), higher modified Charlson Comorbidity Index (p = 0.009), higher potassium (p = 0.02), lower hemoglobin (p = 0.002), and higher lactate (p < 0.001) were associated with death, and diabetes mellitus (p = 0.05), no compartment pressure measurement (p = 0.009), higher PTT (p = 0.03), and lower albumin (p = 0.01) were associated with limb amputation.
conclusionsTime to fasciotomy is not found to be associated with death or limb amputation in acute leg compartment syndrome. Death and limb amputation are associated with patient-related factors and injury severity. LEVEL OF EVIDENCE: Level III Prognostic.
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