ArticleThe EMBO journal2019
Lignin-based barrier restricts pathogens to the infection site and confers resistance in plants.
Article in The EMBO journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 164 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
164 citing papers in PubMed, 401 citations in OpenAlex.
- Functional diversification of CsCAD14 orchestrates synergistic phenylpropanoid biosynthesis to defend gray blight disease in tea plants.Science advances · 2026Article
- SlTCP16 confers disease resistance in tomato via a dual regulatory mechanism involving transcriptional activation and protein interaction with Sl4CL3.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Towards an Omics-Guided Framework for Microbial Biological Control of Fungal and Oomycete Diseases inInternational journal of molecular sciences · 2026Review
- Comparative transcriptomics reveal distinct anthracnose immune pathways in resistant and susceptible Camellia oleifera clones.Pest management science · 2026Article
- CsWRKY33 Integrates Immune Signalling and Metabolic Reprogramming to Enhance Tea Plant Resistance Against Colletotrichum camelliae.Plant, cell & environment · 2026Article
- Article
- Research Advances in Molecular Mechanisms of Xylem Development in Horticultural Plants.Plants (Basel, Switzerland) · 2026Review
- Higher Temperature and Host Age Alter Infection Outcomes in a Multi-Pathogen System.Ecology and evolution · 2026Article
- Metabolomic and Transcriptomic Responses ofPlants (Basel, Switzerland) · 2026Article
- Ethylene signalling enhances mitochondrial stress tolerance independently of the transcription factor ANAC017 in Arabidopsis.Journal of experimental botany · 2026Article
- From Defense Executor to Engineering Target: Harnessing Lignin for Crop Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Phytoplasma Effector SJP8 Suppresses Host Immunity by Promoting the Degradation of ZjMYB15 and ZjMYB86-like to Perturb Jasmonic Acid and Hydrogen Peroxide Homeostasis in Jujube.Molecular plant pathology · 2026Article
- Endophytic mycorrhizal fungi strengthen Lactuca sativa defense against Alternaria alternata as a sustainable biocontrol approach.BMC plant biology · 2026Article
- Integrative Transcriptomic and Biochemical Profiling RevealsPlants (Basel, Switzerland) · 2026Article
- Transcriptome-metabolome integration reveals MYB/WRKY-RGA network and phenylalanine metabolism in potato late blight resistance.BMC plant biology · 2026Article
- Spatial organization of plant defense at the infection front.bioRxiv : the preprint server for biology · 2026Article
- A novel fracture lattice in spiny mouse skin facilitates tissue autotomy and regeneration.bioRxiv : the preprint server for biology · 2026Article
- Time-resolved transcriptome analysis reveals molecular signatures of Fusarium proliferatum DSM106835-induced sudden decline syndrome in date palm (Phoenix dactylifera L.).Journal of experimental botany · 2026Article
- The Zma-miRNA319-ZmMYB74 Module Regulates Maize Resistance to Stalk Rot Disease by Modulating Lignin Deposition.Plant biotechnology journal · 2026Article
- Genome-wide identification, characterization, and expression profile analysis of the caffeic acid O-methyltransferases gene family in sweet orange (Citrus sinensis L.) in response to Penicillium digitatum infection.BMC plant biology · 2026Article
104 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
Abstract
Pathogenic bacteria invade plant tissues and proliferate in the extracellular space. Plants have evolved the immune system to recognize and limit the growth of pathogens. Despite substantial progress in the study of plant immunity, the mechanism by which plants limit pathogen growth remains unclear. Here, we show that lignin accumulates in Arabidopsis leaves in response to incompatible interactions with bacterial pathogens in a manner dependent on Casparian strip membrane domain protein (CASP)-like proteins (CASPLs). CASPs are known to be the organizers of the lignin-based Casparian strip, which functions as a diffusion barrier in roots. The spread of invading avirulent pathogens is prevented by spatial restriction, which is disturbed by defects in lignin deposition. Moreover, the motility of pathogenic bacteria is negatively affected by lignin accumulation. These results suggest that the lignin-deposited structure functions as a physical barrier similar to the Casparian strip, trapping pathogens and thereby terminating their growth.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.