ArticleHeadache2020
Migraine Genetic Variants Influence Cerebral Blood Flow.
Article in Headache, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Potential analgesic effect of Foshousan oil-loaded chitosan-alginate nanoparticles on the treatment of migraine.Frontiers in pharmacology · 2023Article
- Review
- Dynamic cerebral autoregulation across the cardiac cycle during 8 hr of recovery from acute exercise.Physiological reports · 2020Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo investigate the association of migraine genetic variants with cerebral blood flow (CBF).
backgroundMigraine is a common disorder with many genetic and non-genetic factors affecting its occurrence. The exact pathophysiological mechanisms underlying the disease remain unclear, but are known to involve hemodynamic and vascular disruptions. Recent genome-wide association studies have identified 44 genetic variants in 38 genetic loci that affect the risk of migraine, which provide the opportunity to further disentangle these mechanisms.
methodsWe included 4665 participants of the population-based Rotterdam Study (mean age 65.0 ± 10.9 years, 55.6% women). Cross-sectional area (mm
resultsThe rs67338227 risk allele was associated with higher flow velocity and smaller cross-sectional area in the carotids (P
conclusionsThese findings show that genetic migraine risk is complexly associated with alterations in cerebral hemodynamics.
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Registered trials
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