ReviewHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2019
Blood Pressure Variability and Therapeutic Implications in Hypertension and Cardiovascular Diseases.
Review in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed.
- Association of Systolic Blood Pressure Time in Target Range With Cardiovascular Events Among PRECISION Participants.Journal of clinical hypertension (Greenwich, Conn.) · 2025Trial
- Allopurinol and blood pressure variability following ischemic stroke and transient ischemic attack: a secondary analysis of XILO-FIST.Journal of human hypertension · 2024Trial
- Effect of dihydropyridine calcium channel blockers on blood pressure variability in the SPRINT trial: a treatment effects approach.Journal of hypertension · 2022Trial
- A Prospective Comparison of Azilsartan and Amlodipine for Bevacizumab-induced Hypertension and Proteinuria in Colorectal Cancer.In vivo (Athens, Greece)Trial
- Blood pressure variability and cardiovascular risk in pediatric hypertension.Pediatric nephrology (Berlin, Germany) · 2026Article
- Very short-term blood pressure variability by pulse transit time-based measurements during night-time predicts future cardiovascular events in patients with ischemic heart disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Association between meteorological factors and blood pressure variability in northern Guizhou, China.Frontiers in public health · 2026Article
- Aerobic, Resistance, and Isometric Exercise to Reduce Blood Pressure Variability: A Network Meta-Analysis of 15 Clinical Trials.Journal of clinical hypertension (Greenwich, Conn.) · 2025Review
- Blood Pressure Variability and Cognition in Black and White Older Adults Over 18 Years of Follow-up: A Population-Based Cohort Study.Neurology · 2025Observational
- Blood pressure reactivity to mental stress is related to daily blood pressure variability in postmenopausal hypertensive women.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Article
- The Dose-response of Blood Pressure Variability in Stroke and Coronary Heart Disease.Current hypertension reviews · 2025Article
- Short-term blood pressure variability and reduced cytosolic calcium levels.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Physiological Variability during Prehospital Stroke Care: Which Monitoring and Interventions Are Used?Healthcare (Basel, Switzerland) · 2024Review
- Interdialytic home systolic blood pressure variability increases all-cause mortality in hemodialysis patients.Clinical cardiology · 2024Article
- Association Between Elevated Body Mass Index and Cardiac Organ Damage in Children and Adolescents: Evidence and Mechanisms.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024Article
- Blood Pressure Variability and Plasma Biomarkers of Neuronal Injury and Alzheimer's Disease: A Clinic-Based Study of Patients with Diseases Along the Heart-Brain Axis.Journal of Alzheimer's disease : JAD · 2024Article
- Under pressure: A systematic review of the association between blood pressure variability with depression and anxiety.Cerebral circulation - cognition and behavior · 2024Article
- Changes in beat-to-beat blood pressure and pulse rate variability following stroke.Scientific reports · 2023Article
- Blood Pressure Variability in Clinical Practice: Past, Present and the Future.Journal of the American Heart Association · 2023Review
- Twenty-four hour blood pressure variability and the prevalence and the progression of cerebral white matter hyperintensities.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blood pressure (BP) is characterized by continuous dynamic and spontaneous oscillations occurring over lifetime and defining the so-called blood pressure variability (BPV). BPV has been associated with target organ damage, cardiovascular (CV) risk and death, suggesting the use of BPV as a new target in hypertension management in addition to mean BP values lowering. The purpose of the review is to focus on the therapeutic implications of BPV and summarize the effects of different drug classes on various types of BPV. Despite most first-line antihypertensive medications contribute to reduce both short and long term BPV, calcium channel blockers (CCBs) as monotherapy or fixed-combination therapy appear to be the most effective on BPV control. Further randomized interventional trials are needed to investigate which drug combinations are most appropriate according to patient CV risk stratification, in order to improve their CV outcomes.
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