ArticleJournal of experimental botany2020
LAZY3 plays a pivotal role in positive root gravitropism in Lotus japonicus.
Article in Journal of experimental botany, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Working smarter, not harder: silencingHorticulture research · 2025Article
- Exploring plant responses to altered gravity for advancing space agriculture.Plant communications · 2025Review
- Peach LAZY1 and DRO1 protein-protein interactions and co-expression with PRAF/RLD family support conserved gravity-related protein interactions across plants.microPublication biology · 2024Article
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- The Sapria himalayana genome provides new insights into the lifestyle of endoparasitic plants.BMC biology · 2023Article
- Identification ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Tapping into the plasticity of plant architecture for increased stress resilience.F1000Research · 2023Review
- Gravity sensing and responses in the coordination of the shoot gravitropic setpoint angle.The New phytologist · 2022Review
- Blocking Rice Shoot Gravitropism by Altering One Amino Acid in LAZY1.International journal of molecular sciences · 2022Article
- Characterization of a Novel Creeping Tartary Buckwheat (Frontiers in plant science · 2022Article
- LAZY1-LIKE-mediated gravity signaling pathway in root gravitropic set-point angle control.Plant physiology · 2021Review
- Understanding the Intricate Web of Phytohormone Signalling in Modulating Root System Architecture.International journal of molecular sciences · 2021Review
- Settling for Less: Do Statoliths Modulate Gravity Perception?Plants (Basel, Switzerland) · 2020Article
- Review
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
LAZY1 family genes play important roles in both shoot and root gravitropism in plants. Here we report a Lotus japonicus mutant that displays negative gravitropic response in primary and lateral roots. Map-based cloning identified the mutant gene LAZY3 as a functional ortholog of the LAZY1 gene. Mutation of the LAZY3 gene reduced rootward polar auxin transport (PAT) in the primary root, which was also insensitive to the PAT inhibitor N-1-naphthylphthalamic acid. Moreover, immunolocalization of enhanced green fluorescent protein-tagged LAZY3 in L. japonicus exhibited polar localization of LAZY3 on the plasma membrane in root stele cells. We therefore suggest that the polar localization of LAZY3 in stele cells might be required for PAT in L. japonicus root. LAZY3 transcripts displayed asymmetric distribution at the root tip within hours of gravistimulation, while overexpression of LAZY3 under a constitutive promoter in lazy3 plants rescued the gravitropic response in roots. These data indicate that root gravitropism depends on the presence of LAZY3 but not on its asymmetric expression in root tips. Expression of other LAZY genes in a lazy3 background did not rescue the growth direction of roots, suggesting that the LAZY3 gene plays a distinct role in root gravitropism in L. japonicus.
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