Evidence map›Paper›PMID 31559362›Full record

ReviewJournal of the anus, rectum and colon2019

Lewy body constipation.

Ryuji Sakakibara, Hirokazu Doi, Shin Fukudo

Open access · goldAbstract readReview
In one paragraph

Review in Journal of the anus, rectum and colon, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. The mechanisms and management of fecal incontinence in geriatric neurological diseases.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026
    Review
  2. Lewy body diseases and the gut.Molecular neurodegeneration · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Gastrointestinal dysfunction in movement disorders.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  9. Article
  10. Gastrointestinal dysfunction in the synucleinopathies.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021
    Review
  11. Recurrent sigmoid volvulus in a patient with Parkinson's disease.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2020
    Article
  12. Article
  13. Gastrointestinal function in dementia with Lewy bodies: a comparison with Parkinson disease.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Ryuji SakakibaraNeurology, Internal Medicine, Sakura Medical Center, Toho University, Shimoshizu, Japan.
Hirokazu DoiPharmaceutical Unit, Sakura Medical Center, Toho University, Shimoshizu, Japan.
Shin FukudoDepartment of Behavioral Medicine, Graduate School of Medicine, Tohoku University, Sendai, Japan.
Tohoku University · JPToho University · JPToho University Medical Center Sakura Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We systematically reviewed literature regarding "Lewy body constipation", i.e., constipation due to Lewy body diseases (LBD), with minimal neurologic symptoms. Epidemiology and pathology studies showed that LBD can start with constipation alone, mostly due to neuronal loss and appearance of Lewy bodies in the myenteric plexus. Because LBD significantly increases with age, "Lewy body constipation" may also increase with age. Neuroimaging methods such as metaiodobenzylguanidine (MIBG) scintigraphy and dopamine transporter (DAT) scan provide a way to detect "Lewy body constipation." Key for "Lewy body constipation" includes minimal non-motor features such as REM sleep behavior disorder (night talking). Add-on therapy may be required to ameliorate constipation in patients. Diagnosis is not always easy; therefore, collaboration of gastroenterologists and neurologists is highly recommended to maximize patients' quality of life. In conclusion, "Lewy body constipation" might become a distinct category among geriatric constipation, regarding patients' follow-up and their management.

Indexed as

constipationdementia with Lewy bodiesLewy body constipationneuroimagingParkinson's disease

Identifiers

PMID31559362
PMCPMC6752132
OpenAlexW2914111884

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.