Evidence map›Paper›PMID 31559179›Full record

ArticleGland surgery2019

Delayed enhancement in differential diagnosis of salivary gland neoplasm.

Alfonso Reginelli, Alfredo Clemente, Matteo Renzulli, Nicola Maggialetti, Mario Santagata, Giuseppe Colella, Valerio Nardone, Rita Golfieri, Luca Brunese, Salvatore Cappabianca

Abstract read
In one paragraph

Article in Gland surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alfonso ReginelliRadiology and Radiotherapy Unit, Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Alfredo ClementeRadiology and Radiotherapy Unit, Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Matteo RenzulliRadiology Unit, Department of Experimental, Diagnostic and Speciality Medicine, Sant'Orsola Hospital, University of Bologna, Bologna, Italy.
Nicola MaggialettiLife and Health Department "V. Tiberio", University of Molise, Campobasso, Italy.
Mario SantagataMultidisciplinary Department of Medical, Surgical and Dental Specialities, Maxillo-Facial Unit, University of Campania "L. Vanvitelli", Naples, Italy.
Giuseppe ColellaMultidisciplinary Department of Medical, Surgical and Dental Specialities, Maxillo-Facial Unit, University of Campania "L. Vanvitelli", Naples, Italy.
Valerio NardoneUnit of Radiation Oncology, Ospedale del Mare, Naples, Italy.
Rita GolfieriRadiology Unit, Department of Experimental, Diagnostic and Speciality Medicine, Sant'Orsola Hospital, University of Bologna, Bologna, Italy.
Luca BruneseLife and Health Department "V. Tiberio", University of Molise, Campobasso, Italy.
Salvatore CappabiancaRadiology and Radiotherapy Unit, Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMulti-phasic Computed Tomography (CT) evaluation allows to study the enhancement features of parotid gland masses. The aim of our study was to evaluate the role of delayed enhancement in the characterization of different histologic types of parotid tumours.

methodsForty-eight patients (22 male and 26 female) with at least one parotid gland tumor, were included in our study. Multi-phase CT images were obtained before and 30, 120 s and 8 minutes after intravenous contrast injection. The images were evaluated by two radiologists for lesion enhancement degree. A quantitative assessment was performed using a region of interest on each lesion and density changes between different phases were compared. The tumoral enhancement ratio was calculated between the 8 minutes delayed and the early (30 s) phase. The pathological diagnosis was confirmed in all patients after surgery.

resultsAll patients had unilateral lesion for a total of 48 lesions. Twenty-eight were pleomorphic adenomas, 15 Warthin's tumours and 5 carcinomas. All Warthin tumours showed a rapid contrast enhancement at the early phase (30 sec) followed by a progressive wash-out during the delayed scans. Most of pleomorphic adenomas (89.2%) showed the highest density at the 8-minutes delayed phase. Malignant tumours showed slower contrast enhancement and 3 out of 5 (60%) showed a marked decrease at the 8 minutes delayed phase while the remaining 2 (40%), did not show any density reduction. The tumoral enhancement ratio was significantly different between Warthin tumours and pleomorphic adenomas and between Warthin's and malignant tumours.

conclusionsMulti-phasic CT examination with 8 minutes delayed acquisition has shown to be useful in parotid gland lesion differentiation.

Indexed as

computed tomographyneoplasmParotid gland

Identifiers

PMID31559179
PMCPMC6755945

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.