ArticleJournal of thoracic disease2019
Outcomes and risk factors of postoperative hepatic dysfunction in patients undergoing acute type A aortic dissection surgery.
Article in Journal of thoracic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04271098 (Risk Factors, Hepatic Dysfunction, and Open-heart Surgery), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Risk Factors, Hepatic Dysfunction, and Open-heart Surgery
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Risk factors and prognosis of postoperative hepatic dysfunction after Stanford type A aortic dissection repair: a systematic review and meta-analysis.Journal of cardiothoracic surgery · 2026Pooled it
- Effect of preoperative model for end-stage liver disease score in cardiac valve surgery.General thoracic and cardiovascular surgery · 2026Article
- Prognostic value of postoperative albumin-bilirubin score in patients with acute type A aortic dissection after surgery: a propensity-score matched analysis.BMC cardiovascular disorders · 2026Article
- Nomogram prediction of acute kidney injury following modified Morrow myectomy in hypertrophic obstructive cardiomyopathy: insights from 12 years of outcomes.BMC cardiovascular disorders · 2026Article
- Admission creatinine level predicts postoperative acute hepatic dysfunction in patients aged ≤30 years with acute type A aortic dissection: a multi-center retrospective study.Frontiers in cardiovascular medicine · 2026Article
- Effects of Ulinastatin on Inflammation Response and Lung Tissue Injury in Deep Hypothermic Circulatory Arrest.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
- Analysis of risk factors and linear prediction model construction for prolonged mechanical ventilation after Stanford A-type aortic dissection.Frontiers in surgery · 2025Article
- Prognostic value of preoperative MELD-albumin score in patients undergoing heart transplant.Frontiers in cardiovascular medicine · 2025Article
- Association of Preoperative Leukocyte-to-Albumin Ratio with Short- and Long-Term Outcomes After Valvular Heart Surgery: A Retrospective Cohort Study.Journal of inflammation research · 2025Article
- The geriatric nutritional risk index is related to adverse hospitalization outcomes in individuals undergoing cardiac surgery.Scientific reports · 2024Article
- Application of model for end-stage liver disease as disease classification in cardiac valve surgery: a retrospective study based on the INSPIRE database.Journal of thoracic disease · 2024Article
- Article
- Prevalence and clinical relevance of liver dysfunction after thoracic surgery: a retrospective study.Scientific reports · 2023Article
- The blood glucose-potassium ratio at admission predicts in-hospital mortality in patients with acute type A aortic dissection.Scientific reports · 2023Article
- Analysis of Prognosis and Risk Factors for Postoperative Hepatic Dysfunction in Patients with Acute Type A Aortic Dissection.Anatolian journal of cardiology · 2023Article
- Persistent Liver Dysfunction in Pediatric Patients After Total Cavopulmonary Connection Surgery.Frontiers in cardiovascular medicine · 2022Article
- Hepatic dysfunction in patients who received acute DeBakey type I aortic dissection repair surgery: incidence, risk factors, and long-term outcomes.Journal of cardiothoracic surgery · 2021Article
- The risk factors and outcomes of preoperative hepatic dysfunction in patients who receive surgical repair for acute type A aortic dissection.Journal of thoracic disease · 2021Article
- Investigation of Risk Factors Related to the Development of Hepatic Dysfunction in Patients with a Low and Moderate Cardiac Risk During Open-Heart Surgeries.Brazilian journal of cardiovascular surgery · 2021Article
- Development and Validation of a Diagnostic Model to Predict the Risk of Ischemic Liver Injury After Stanford A Aortic Dissection Surgery.Frontiers in cardiovascular medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative hepatic dysfunction (HD) increases the morbidity and mortality risk after cardiac surgery; however, only a few studies have specifically focused on acute type A aortic dissection (AAAD) surgery. We explored the possible risk factors and outcomes of early postoperative HD in patients with AAAD undergoing surgery.
methodsAll patients who underwent AAAD surgery at our institution from April 2015 to April 2017 were retrospectively evaluated. Postoperative model for end-stage liver disease (MELD) score was used to define HD. Independent risk factors for HD were determined by multivariate logistic analysis.
resultsTwo hundred fifteen patients with AAAD met the inclusion criteria. The incidence rate of early postoperative HD was 60.9%, and the rate of in-hospital mortality was 16.8%. Patients with a high postoperative MELD score had longer mechanical ventilation time, longer durations of intensive care unit (ICU) stay, and higher in-hospital mortality. During the postoperative period, patients with AAAD complicated by HD needed continuous renal replacement therapy (CRRT), reintubation, tracheostomy, and blood transfusion more frequently. Aortic cross clamp (ACC) time [per 10 min higher; odds ratio (OR): 1.216, 95% confidence interval (CI): 1.017-1.454, P=0.032], postoperative leucocytes (per 2×10
conclusionsPostoperative HD prolongs mechanical ventilation time and ICU stay, and is associated with increased in-hospital mortality among patients who undergo AAAD surgery. Several factors are associated with a high postoperative MELD score.
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