Evidence map›Paper›PMID 31558924›Full record

ArticleThe Pan African medical journal2019

Human papillomavirus correlates of high grade cervical dysplasia among HIV-Infected women at a major treatment centre in Nigeria: a cross-sectional study.

Martin Maimako Yakub, Adeola Fowotade, Chinenye Gloria Anaedobe, Mohammed Mohammed Manga, Rasheed Ajani Bakare, Bawa Ahmed Abimiku

Abstract read
In one paragraph

Article in The Pan African medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 6 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Martin Maimako YakubDepartment of Medical Microbiology and Parasitology, University College Hospital, Ibadan, Nigeria.
Adeola FowotadeDepartment of Medical Microbiology and Parasitology, University College Hospital, Ibadan, Nigeria.
Chinenye Gloria AnaedobeDepartment of Medical Microbiology and Parasitology, University College Hospital, Ibadan, Nigeria.
Mohammed Mohammed MangaDepartment of Medical Microbiology and Parasitology, University College Hospital, Ibadan, Nigeria.
Rasheed Ajani BakareDepartment of Medical Microbiology and Parasitology, University College Hospital, Ibadan, Nigeria.
Bawa Ahmed AbimikuDepartment of Histopathology and Forensic Medicine, Gwagwalada Teaching Hospital, Abuja, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPersistent high-risk HPV (hrHPV) infection is higher among women living with HIV/AIDS thus increasing their risk for cervical cancer. We evaluated the virological and immunological correlates of cervical dysplasia in HIV-infected women.

methodsA cohort of 220 consenting women attending the antiretroviral clinic of the Federal Medical Centre, Keffi, Nigeria was tested for cervical human papilloma virus (HPV) infection using PCR. The prevalent HPV genotypes were determined by DNA sequencing. CD4+T count and type specific HPV was correlated with cervical cytology. Descriptive and inferential statistical analysis of the data was done using the statistical package for social sciences (SPSS) version 20 (SPSS Inc, Illinois, USA) for analysis after validation.

resultsOverall HPV prevalence was 54.1% while the hrHPV prevalence was 35.9%. Premalignant and malignant lesions were observed among participants with CD4+T counts between 200-300/mm

conclusionRisk stratification with HPV screening among HIV-infected women will help in early case management of cervical precancerous lesions.

Indexed as

AdultAgedCD4 Lymphocyte CountCohort StudiesCross-Sectional StudiesFemaleHIV InfectionsHumansMass ScreeningMiddle AgedNigeriaPapillomaviridaePapillomavirus InfectionsPrevalenceUterine Cervical DysplasiagenotypesHIV-positive womenHuman papillomavirusNigeriapremalignant lesionsuterine cervix

Identifiers

PMID31558924
PMCPMC6754827

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.