Evidence map›Paper›PMID 31558855›Full record

ReviewWorld journal of gastroenterology2019

Diagnostic and prognostic potential of tissue and circulating long non-coding RNAs in colorectal tumors.

Orsolya Galamb, Barbara K Barták, Alexandra Kalmár, Zsófia B Nagy, Krisztina A Szigeti, Zsolt Tulassay, Peter Igaz, Béla Molnár

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 2 syntheses or guidelines pooled it, 109 citations in OpenAlex.

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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Orsolya GalambMolecular Medicine Research Group, Hungarian Academy of Sciences, Budapest H-1088, Hungary. udvardyne_galamb.orsolya@semmelweis-univ.hu.
Barbara K Barták2 Department of Internal Medicine, Semmelweis University, Budapest H-1088, Hungary.
Alexandra KalmárMolecular Medicine Research Group, Hungarian Academy of Sciences, Budapest H-1088, Hungary.
Zsófia B Nagy2 Department of Internal Medicine, Semmelweis University, Budapest H-1088, Hungary.
Krisztina A Szigeti2 Department of Internal Medicine, Semmelweis University, Budapest H-1088, Hungary.
Zsolt TulassayMolecular Medicine Research Group, Hungarian Academy of Sciences, Budapest H-1088, Hungary.
Peter IgazMolecular Medicine Research Group, Hungarian Academy of Sciences, Budapest H-1088, Hungary.
Béla MolnárMolecular Medicine Research Group, Hungarian Academy of Sciences, Budapest H-1088, Hungary.
Semmelweis University · HUHungarian Academy of Sciences · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) are members of the non-protein coding RNA family longer than 200 nucleotides. They participate in the regulation of gene and protein expression influencing apoptosis, cell proliferation and immune responses, thereby playing a critical role in the development and progression of various cancers, including colorectal cancer (CRC). As CRC is one of the most frequently diagnosed malignancies worldwide with high mortality, its screening and early detection are crucial, so the identification of disease-specific biomarkers is necessary. LncRNAs are promising candidates as they are involved in carcinogenesis, and certain lncRNAs (

Indexed as

Biomarkers, TumorBiopsyCarcinogenesisCell-Free Nucleic AcidsColonColorectal NeoplasmsDisease-Free SurvivalDisease ProgressionGene Expression Regulation, NeoplasticHumansNeoplasm StagingPrognosisRectumRNA, Long NoncodingBiomarkers, TumorCell-Free Nucleic AcidsRNA, Long NoncodingBiomarkerCirculating long non-coding RNAsColorectal adenomaColorectal cancerDiagnostic markerExosomeLong non-coding RNAPrognostic marker

Identifiers

PMID31558855
PMCPMC6747286
OpenAlexW2973099653

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.