Evidence map›Paper›PMID 31558775›Full record

ArticleThe Journal of antibiotics2019

Muraminomicins, novel ester derivatives: in vitro and in vivo antistaphylococcal activity.

Yoshiko Kagoshima, Akane Tokumitsu, Takeshi Masuda, Eiko Namba, Harumi Inoue, Chika Sugihara, Mizuka Yokoyama, Yuko Yamamoto, Keiko Suzuki, Kouki Iida and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in The Journal of antibiotics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yoshiko KagoshimaMedicinal Chemistry Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Akane TokumitsuBiological Research Laboratories, Sankyo Co., Ltd., Tokyo, Japan.
Takeshi MasudaBiologics Technology Research Laboratories, Daiichi Sankyo Co., Ltd., Gunma, Japan.
Eiko NambaVaccine Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Harumi InoueTechnology Department, Daiichi Sankyo Biotec Co., Ltd., Saitama, Japan.
Chika SugiharaBiologic Research Department, Daiichi Sankyo RD Novare Co., Ltd., Tokyo, Japan.
Mizuka YokoyamaMedical Science Department, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Yuko YamamotoProcess Technology Research Laboratories, Daiichi Sankyo Co., Ltd., Kanagawa, Japan.
Keiko SuzukiMedicinal Chemistry Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Kouki IidaProcess Technology Research Laboratories, Daiichi Sankyo Co., Ltd., Kanagawa, Japan.
Akihiro TamuraOrganic Synthesis Department, Daiichi Sankyo RD Novare Co., Ltd., Tokyo, Japan.
Yoko FujitaOrganic Synthesis Department, Daiichi Sankyo RD Novare Co., Ltd., Tokyo, Japan.
Toshio TakatsuOrganic Synthesis Department, Daiichi Sankyo RD Novare Co., Ltd., Tokyo, Japan.
Toshiyuki KonosuResearch Function, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Tetsufumi KogaVaccine Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan. koga.tetsufumi.zj@daiichisankyo.co.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel muraminomicin derivatives with antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA) were synthesized by esterification of the hydroxy group on the diazepanone ring of muraminomicin Z

Indexed as

AnimalsAnti-Bacterial AgentsBacterial ProteinsDrug Evaluation, PreclinicalHumansMagnetic Resonance SpectroscopyMaleMethicillin-Resistant Staphylococcus aureusMice, Inbred StrainsMicrobial Sensitivity TestsMutation RateStaphylococcal InfectionsStaphylococcus aureusTransferasesTransferases (Other Substituted Phosphate Groups)Anti-Bacterial AgentsBacterial ProteinsmraY protein, BacteriaTransferasesTransferases (Other Substituted Phosphate Groups)

Identifiers

PMID31558775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.