ArticleThe Journal of experimental medicine2019
CXCR6 regulates localization of tissue-resident memory CD8 T cells to the airways.
Open access · bronzeAbstract read
In one paragraph
Article in The Journal of experimental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 235 papers.
0numbers the graph read from it
0cells of the map it votes in
235citing papers in PubMed
15.5field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
235 citing papers in PubMed, 344 citations in OpenAlex.
- Trial
- Viral genomic, metagenomic and human transcriptomic characterization and prediction of the clinical forms of COVID-19.PLoS pathogens · 2021Trial
- Respiratory mucosal immunity: Biological functions, diseases, prevention and therapy.Genes & diseases · 2026Review
- Review
- CD8⁺ T Cell infiltration and spatial organization in cancer: mechanisms, barriers, and therapeutic strategies.Molecular biomedicine · 2026Review
- Barrier immune memory is programmed by intestinal epithelial cell presentation of cytosol-delivered bacterial antigens.Nature immunology · 2026Article
- Single-cell RNA sequencing reveals clonally expanded CD4+ tissue-resident memory T cells in histidyl-tRNA synthetase-induced myositis.JCI insight · 2026Article
- Cardiac tertiary immune niches drive immune activation in immune checkpoint inhibitor myocarditis.Science advances · 2026Article
- Dynamic remodeling of the pancreas immune landscape in obesity.Nature communications · 2026Article
- CXCR6 marks polyfunctional effector CD4 T cells required for anti-bioRxiv : the preprint server for biology · 2026Article
- Ovarian localization drives IL-7R-dependent CD8 coreceptor expression in peripheral double-negative T cells.Cellular and molecular life sciences : CMLS · 2026Article
- CD49aScientific reports · 2026Article
- Heterogeneity and dynamics of DENV-specific CD8 + T cells in dengue infection.Nature communications · 2026Article
- PD-1 Inhibits CD4+ TRM-Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Glycolysis-driven cancer-associated fibroblasts shape T-Cell exclusion via the CXCL16-CXCR6 Axis: a metabolic-chemokine mechanism in tumor immunity.Journal of translational medicine · 2026Review
- Highly focused human CD8+ T-cell response in the lower airways during acute influenza infection.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Cross-reactive tissue-resident memory T lymphocytes-concepts, evidence, and open questions.Journal of translational medicine · 2026Review
- Nasal CD4+ tissue-resident memory T cells provide cross-protective immunity to influenza.The Journal of experimental medicine · 2026Article
- Chemokine-chemokine receptor axis: Emerging immunotherapeutic paradigms for solid tumor microenvironment reprogramming.Chinese medical journal · 2026Review
- HIF-1αImmunity · 2026Article
175 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 5 institutions in 2 countries.
Alexander N Wein *Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-8813-3523
Sean R McMaster *Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA.
Shiki Takamura *Department of Immunology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.ORCID 0000-0001-6681-0258
Paul R DunbarDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-9082-6636
Emily K CartwrightDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA.
Sarah L HaywardDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0001-7052-5556
Daniel T McManusDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA.
Takeshi ShimaokaDivision of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Noda, Chiba, Japan.
Satoshi UehaDivision of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Noda, Chiba, Japan.
Tatsuya TsukuiDepartment of Medicine, University of California, San Francisco, San Francisco, CA.
Tomoko MasumotoDepartment of Immunology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.
Makoto KurachiDepartment of Microbiology and Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Kouji MatsushimaDivision of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Noda, Chiba, Japan.
Jacob E KohlmeierDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA jkohlmeier@emory.edu.ORCID 0000-0002-7209-6641
Emory University · USTokyo University of Science · JPKindai University · JPUniversity of California, San Francisco · USUniversity of Pennsylvania · US
Funding
MEDICAL SCIENTIST TRAINING PROGRAMT32GM008169 · NIGMS · EMORY UNIVERSITY · PI GROSS, ROBERT E · 1987 to 2021
$20.3MTRAINING IN IMMUNOLOGY AND MOLECULAR PATHOGENESIST32AI007610 · NIAID · EMORY UNIVERSITY · PI EVAVOLD, BRIAN D · 2000 to 2014
$4.4MImprinting of Lung-Resident T Cell MemoryR01HL122559 · NHLBI · EMORY UNIVERSITY · PI KOHLMEIER, JACOB E · 2015 to 2019
$1.9MRegulation of lung TRM maintenance and the decline of pulmonary cellular immunityR01HL138508 · NHLBI · EMORY UNIVERSITY · PI KOHLMEIER, JACOB E · 2017 to 2019
$1.2MThe Role of CXCR6 in Lung Airway Memory T cell Recruitment and MaintenanceF30HL118954 · NHLBI · EMORY UNIVERSITY · PI MCMASTER, SEAN R · 2014 to 2016
$142kThe role of APC's in the establishment of lung tissue resident memory T CellsF31AI124611 · NIAID · EMORY UNIVERSITY · PI DUNBAR, PAUL RICHARD · 2016 to 2018
$132kIdentifying mechanisms of lung tissue-resident memory CD8 T cell decayF31HL136101 · NHLBI · EMORY UNIVERSITY · PI HAYWARD, SARAH LOUISE · 2017 to 2019
$110kNHLBI NIH HHS F30 HL118954NHLBI NIH HHS F31 HL136101NHLBI NIH HHS R01 HL122559NHLBI NIH HHS R01 HL138508NIAID NIH HHS F31 AI124611NIAID NIH HHS HHSN272201300006CNIAID NIH HHS HHSN272201400004CNIAID NIH HHS T32 AI007610NIGMS NIH HHS T32 GM008169
Abstract
Resident memory T cells (T
Indexed as
Immunologic MemoryImmunomodulationAnimalsCD8-Positive T-LymphocytesGene ExpressionHumansImmunophenotypingMiceMice, KnockoutProtein BindingReceptors, CXCR6Respiratory MucosaT-Cell Antigen Receptor SpecificityReceptors, CXCR6
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.