Evidence map›Paper›PMID 31558607›Full record

ArticleThe Journal of biological chemistry2019

Julius Benicky, Miloslav Sanda, Zuzana Brnakova Kennedy, Radoslav Goldman

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Julius BenickyDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, D. C. 20057.ORCID 0000-0002-1941-1622
Miloslav SandaDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, D. C. 20057.
Zuzana Brnakova KennedyDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, D. C. 20057.
Radoslav GoldmanDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, D. C. 20057 rg26@georgetown.edu.
Georgetown University · USGeorgetown University Medical Center · US

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI STEPHEN W BYERS · 1990 to 2026
$71.5M
Glycans in Hepatocellular CarcinomaR01CA135069 · NCI · GEORGETOWN UNIVERSITY · PI GOLDMAN, RADOSLAV · 2009 to 2019
$4.1M
O-glycoproteins in the progression of liver diseaseR01CA238455 · NCI · GEORGETOWN UNIVERSITY · PI GOLDMAN, RADOSLAV · 2019 to 2023
$2.6M
Alliance of Glycobiologists for Detection of CancerU01CA168926 · NCI · GEORGETOWN UNIVERSITY · PI GOLDMAN, RADOSLAV · 2012 to 2016
$2.0M
LC-MS Analysis of Site Specific Protein GlycoformsU01CA230692 · NCI · GEORGETOWN UNIVERSITY · PI EDWARDS, NATHAN J, GOLDMAN, RADOSLAV · 2018 to 2020
$1.3M
Orbitrap Fusion Lumos ETDS10OD023557 · OD · GEORGETOWN UNIVERSITY · PI GOLDMAN, RADOSLAV · 2017 to 2017
$1.1M
NCI NIH HHS P30 CA051008NCI NIH HHS R01 CA135069NCI NIH HHS R01 CA238455NCI NIH HHS U01 CA168926NCI NIH HHS U01 CA230692NIH HHS S10 OD023557
6 · The paper itself

Abstract

Brain-derived neurotrophic factor (BDNF) is generated by proteolytic cleavage of a prodomain from the proBDNF precursor either intracellularly by furin-like proteases or extracellularly by plasmin or matrix metalloproteinases. ProBDNF carries a single

Indexed as

Amino Acid SequenceAnimalsBrain-Derived Neurotrophic FactorGlycosylationHEK293 CellsHumansLactoseProtein PrecursorsSulfatesBrain-Derived Neurotrophic Factorbrain-derived neurotrophic factor precursorLactoseN-acetylgalactosaminyl-1-4-N-acetylglucosamineProtein PrecursorsSulfatesbrain-derived neurotrophic factor (BDNF)glycoproteinglycosylationLacdiNAcmass spectrometry (MS)maturationN121Qneurotrophinsulfation

Identifiers

PMID31558607
PMCPMC6851326
OpenAlexW2977154009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.