Evidence map›Paper›PMID 31558583›Full record

ArticleGenetics2019

Stress-Induced Neuron Remodeling Reveals Differential Interplay Between Neurexin and Environmental Factors in

Michael P Hart

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Antioxidants, Hormetic Nutrition, and Autism.Current neuropharmacology · 2024
    Review
  9. Conserved autism-associated genes tune social feeding behavior inbioRxiv : the preprint server for biology · 2023
    Article
  10. Article
  11. Article
  12. Homeostatic Roles of the Proteostasis Network in Dendrites.Frontiers in cellular neuroscience · 2020
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Michael P HartDepartment of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania 19104 hartmic@pennmedicine.upenn.edu.ORCID 0000-0001-8865-3062
University of Pennsylvania · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Neurexins are neuronal adhesion molecules important for synapse maturation, function, and plasticity. Neurexins have been genetically associated with neurodevelopmental disorders, including autism spectrum disorders (ASDs) and schizophrenia, but can have variable penetrance and phenotypic severity. Heritability studies indicate that a significant percentage of risk for ASD and schizophrenia includes environmental factors, highlighting a poorly understood interplay between genetic and environmental factors. The singular

Indexed as

Stress, PhysiologicalAgingAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell Adhesion Molecules, NeuronalGABAergic NeuronsMaleModels, BiologicalNeuronal OutgrowthNeuronal PlasticityPresynaptic TerminalsCaenorhabditis elegans ProteinsCell Adhesion Molecules, Neuronalneuroligin 1nrx-1 protein, C elegansCaenorhabditis elegansneurexinneuronneuroscienceplasticitystress

Identifiers

PMID31558583
PMCPMC6893388
OpenAlexW2976720644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.