Evidence map›Paper›PMID 31558570›Full record

ReviewDevelopment (Cambridge, England)2019

EvoChromo: towards a synthesis of chromatin biology and evolution.

Ines A Drinnenberg, Frédéric Berger, Simon J Elsässer, Peter R Andersen, Juan Ausió, Wendy A Bickmore, Alexander R Blackwell, Douglas H Erwin, James M Gahan, Brandon S Gaut and 18 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Chromatin enables precise and scalable gene regulation with factors of limited specificity.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Meiotic drive of noncentromeric loci in mammalian meiosis II eggs.Current opinion in genetics & development · 2023
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 20 institutions in 11 countries.

Ines A DrinnenbergInstitut Curie, Paris Sciences et Lettres Research University, Centre National de la Recherche Scientifique UMR 3664, Paris 75005, France ines.drinnenberg@curie.fr frederic.berger@gmi.oeaw.ac.at.
Frédéric BergerGregor Mendel Institute, Austrian Academy of Sciences, Vienna BioCenter, Dr. Bohr-Gasse 3, 1030 Vienna, Austria ines.drinnenberg@curie.fr frederic.berger@gmi.oeaw.ac.at.ORCID 0000-0002-3609-8260
Simon J ElsässerScience for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 17177, Sweden.
Peter R AndersenInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Dr. Bohrgasse 3, 1030 Vienna, Austria.ORCID 0000-0001-5815-4860
Juan AusióDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8W 3P6, Canada.
Wendy A BickmoreMedical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.ORCID 0000-0001-6660-7735
Alexander R BlackwellDepartment of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, UK.
Douglas H ErwinDepartment of Paleobiology, MRC-121, National Museum of Natural History, Washington, DC 20013-7012, USA.
James M GahanSars Centre for Marine Molecular Biology, University of Bergen, Thormøhlensgt. 55, 5008 Bergen, Norway.
Brandon S GautDepartment of Ecology and Evolutionary Biology, University of California, Irvine, Irvine, CA 92697, USA.
Zachary H HarveyDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Steven HenikoffDivision of Basic Sciences and Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Joyce Y KaoCenter for Genomics and Systems Biology, New York University, 12 Waverly Place, New York, NY 10003, USA.
Siavash K KurdistaniDepartment of Biological Chemistry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.
Bernardo LemosProgram in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
Mia T LevineDepartment of Biology, Epigenetics Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Karolin LugerHoward Hughes Medical Institute and Department of Biochemistry, CU Boulder, Boulder, CO 80303, USA.
Harmit S MalikDivision of Basic Sciences and Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
José M Martín-DuránQueen Mary University of London, School of Biological and Chemical Sciences, Mile End Road, London E1 4NS, UK.
Catherine L PeichelInstitute of Ecology and Evolution, University of Bern, 3012 Bern, Switzerland.
Marilyn B RenfreeSchool of BioSciences, The University of Melbourne, Melbourne, 3010 VIC, Australia.
Kinga RutowiczInstitute of Plant and Microbial Biology, Zurich-Basel Plant Science Center, University of Zurich, 8092 Zürich, Switzerland.
Peter SarkiesMRC London Institute of Medical Sciences and Institute of Clinical Sciences, IMperial College London, Du Cane Road, London W12 0NN, UK.ORCID 0000-0003-0279-6199
Robert J SchmitzDepartment of Genetics, University of Georgia, Athens, GA 30602, USA.
Ulrich TechnauDepartment for Molecular Evolution and Development, Centre of Organismal Systems Biology, University of Vienna, Vienna A-1090, Austria.
Joseph W ThorntonDepartment of Human Genetics, and Department of Ecology and Evolution, University of Chicago, Chicago, IL 60637 USA.
Tobias WarneckeMRC London Institute of Medical Sciences and Institute of Clinical Sciences, IMperial College London, Du Cane Road, London W12 0NN, UK.ORCID 0000-0002-4936-5428
Kenneth H WolfeConway Institute and School of Medicine, University College Dublin, Dublin 4, Ireland.ORCID 0000-0003-4992-4979
Howard Hughes Medical Institute · USMRC London Institute of Medical Sciences · GBETH Zurich · CHGregor Mendel Institute of Molecular Plant Biology · ATInstitute of Genetics and Cancer · GBInstitute of Molecular Biotechnology · ATNational Museum of Natural History · USQueen Mary University of London · GBScience for Life Laboratory · SEStanford University · USThe University of Melbourne · AUUniversité Paris Sciences et Lettres · FRUniversity College Dublin · IEUniversity of Bergen · NOUniversity of Bern · CHUniversity of California, Irvine · USUniversity of California, Los Angeles · USUniversity of Cambridge · GBUniversity of Chicago · USUniversity of Georgia · US

Funding

Genetic Conflict Shapes Centromeres and HeterochromatinR01GM074108 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI MALIK, HARMIT S. · 2005 to 2022
$6.1M
Dynamics of Histone Acetylation in Cancer Cell PhysiologyR01CA178415 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KURDISTANI, SIAVASH · 2013 to 2017
$1.6M
Molecular Pharmacology Training GrantT32GM113854 · NIGMS · STANFORD UNIVERSITY · PI MOCHLY-ROSEN, DARIA · 2015 to 2019
$1.1M
Prevention of Post-Prandial Hypoglycemia Using n-3/n-6 PUFA in PCOSR21AT003401 · NCCIH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KARAKAS, SIDIKA E · 2007 to 2009
$600k
Cryptic genetic variation in the development of sexual traitsF32GM116321 · NIGMS · NEW YORK UNIVERSITY · PI KAO, JOYCE Y · 2016 to 2017
$115k
Austrian Science Fund FWF P 30802Howard Hughes Medical InstituteMedical Research Council MC_UP_1102/7Medical Research Council MC_UU_00007/2NCCIH NIH HHS R21 AT003401NCI NIH HHS R01 CA178415NIGMS NIH HHS F32 GM116321NIGMS NIH HHS R01 GM074108NIGMS NIH HHS T32 GM113854
6 · The paper itself

Abstract

Over the past few years, interest in chromatin and its evolution has grown. To further advance these interests, we organized a workshop with the support of The Company of Biologists to debate the current state of knowledge regarding the origin and evolution of chromatin. This workshop led to prospective views on the development of a new field of research that we term 'EvoChromo'. In this short Spotlight article, we define the breadth and expected impact of this new area of scientific inquiry on our understanding of both chromatin and evolution.

Indexed as

Evolution, MolecularAnimalsChromatinGenomeHumansChromatinChromatinEvoChromoEvolution

Identifiers

PMID31558570
PMCPMC7376748
OpenAlexW2977098036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.