Evidence map›Paper›PMID 31558503›Full record

ArticleAJNR. American journal of neuroradiology2019

Carotid Intraplaque-Hemorrhage Volume and Its Association with Cerebrovascular Events.

L Saba, G Micheletti, W Brinjikji, P Garofalo, R Montisci, A Balestrieri, J S Suri, J K DeMarco, G Lanzino, R Sanfilippo

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

L SabaFrom the Departments of Radiology (L.S., G.M., P.G., A.B.) lucasaba@tiscali.it.ORCID 0000-0003-2870-3771
G MichelettiFrom the Departments of Radiology (L.S., G.M., P.G., A.B.).ORCID 0000-0001-8721-3049
W BrinjikjiDepartments of Radiology (W.B.).ORCID 0000-0001-5271-5524
P GarofaloFrom the Departments of Radiology (L.S., G.M., P.G., A.B.).ORCID 0000-0002-8939-5461
R MontisciVascular Surgery (R.M., R.S.), Azienda Ospedaliero Universitaria, Monserrato (Cagliari), Italy.ORCID 0000-0001-6308-8562
A BalestrieriFrom the Departments of Radiology (L.S., G.M., P.G., A.B.).ORCID 0000-0003-1864-3381
J S SuriStroke Monitoring and Diagnostic Division (J.S.S.), AtheroPoint, Roseville, California.ORCID 0000-0001-6499-396X
J K DeMarcoDepartment of Radiology (J.K.D.), Walter Reed Medical Center, Bethesda, Maryland.ORCID 0000-0001-6434-0010
G LanzinoNeurosurgery (G.L.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0003-1479-465X
R SanfilippoVascular Surgery (R.M., R.S.), Azienda Ospedaliero Universitaria, Monserrato (Cagliari), Italy.ORCID 0000-0003-1307-3674

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeOur aim was to assess the relationship between volume and percentage of intraplaque hemorrhage measured using CT and the occurrence of cerebrovascular events at the time of CT. MATERIALS AND

methodsOne-hundred-twenty-three consecutive subjects (246 carotid arteries) with a mean age of 69 years who underwent CTA were included in this retrospective study. Plaque volume of components and subcomponents (including intraplaque hemorrhage volume) was quantified with dedicated software.

resultsForty-six arteries were excluded because no plaque was identified. In the remaining 200 carotid arteries, a statistically significant difference was found between presentation with cerebrovascular events and lipid volume (

conclusionsResults of our study suggest that Hounsfield unit values <25 have a statistically significant association with the presence of cerebrovascular events and that the ratio intraplaque hemorrhage/lipid volume represents a strong parameter for the association of cerebrovascular events.

Indexed as

AgedCarotid StenosisCerebral HemorrhageCerebrovascular DisordersFemaleHumansMaleMiddle AgedPlaque, AtheroscleroticRetrospective StudiesROC Curve

Identifiers

PMID31558503
PMCPMC7028561

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.