ArticleAJNR. American journal of neuroradiology2019
Multinodular and Vacuolating Posterior Fossa Lesions of Unknown Significance.
Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- Multinodular and vacuolating neuronal tumor: magnetic resonance imaging features.Acta neurologica Belgica · 2026Article
- Radiologic characterization and clinical management of multinodular and vacuolating neuronal tumor (MVNT): a retrospective institutional cohort study.Journal of neuro-oncology · 2025Article
- Multinodular and Vacuolating Neuronal Tumors: Imaging Features, Diagnosis, and Management Challenges.Diagnostics (Basel, Switzerland) · 2025Review
- Multinodular and vacuolating posterior fossa lesions of unknown significance: a long-term observational study and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Observational
- Multinodular Vacuolating Neuronal Tumors: Symptomatic Presentation Versus Incidental Finding: Case Series and Literature Review.Reports (MDPI) · 2024Article
- Vermian multinodular and vacuolating lesion of unknown significance discovered following syncope: a case report.Annals of medicine and surgery (2012) · 2024Article
- Multinodular and Vacuolating Neuronal Tumor-like Lesion of the Spinal Cord: Two Case Reports.AJNR. American journal of neuroradiology · 2024Article
- Case report: Rare case of multinodular and vacuolar neuronal tumors in the cerebellum.Frontiers in neurology · 2023Article
- A rare cause of adult's epileptic crisis: Infratentorial multinodular and vacuolating neuronal tumor.Radiology case reports · 2022Article
- The 2021 World Health Organization Classification of Tumors of the Central Nervous System: What Neuroradiologists Need to Know.AJNR. American journal of neuroradiology · 2022Review
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Authors and funding
36 authors at 20 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multinodular and vacuolating neuronal tumor of the cerebrum is a rare supratentorial brain tumor described for the first time in 2013. Here, we report 11 cases of infratentorial lesions showing similar striking imaging features consisting of a cluster of low T1-weighted imaging and high T2-FLAIR signal intensity nodules, which we referred to as multinodular and vacuolating posterior fossa lesions of unknown significance. No relationship was found between the location of the lesion and clinical symptoms. A T2-FLAIR hypointense central dot sign was present in images of 9/11 (82%) patients. Cortical involvement was present in 2/11 (18%) of patients. Only 1 nodule of 1 multinodular and vacuolating posterior fossa lesion of unknown significance showed enhancement on postcontrast T1WI. DWI, SWI, MRS, and PWI showed no malignant pattern. Lesions did not change in size or signal during a median follow-up of 3 years, suggesting that multinodular and vacuolating posterior fossa lesions of unknown significance are benign malformative lesions that do not require surgical intervention or removal.
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