Evidence map›Paper›PMID 31558450›Full record

ArticleBMJ open2019

Effectiveness of combined eccentric and concentric exercise over traditional cardiac exercise rehabilitation programme in patients with chronic heart failure: protocol for a randomised controlled study.

Guillaume Plaquevent-Hostache, Julianne Touron, Frédéric Costes, Hélène Perrault, Guillaume Clerfond, Christine Cuenin, Andreea Moisa, Bruno Pereira, Marie-Claire Boiteux, Romain Eschalier and 1 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03716778 (Enhanced Effectiveness of Combined Eccentric and Concentric Exercise Over Traditional Cardiac Exercise Rehabilitation Program in Patients With Chronic Heart Failure), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03716778 naterminatednot on this map

Enhanced Effectiveness of Combined Eccentric and Concentric Exercise Over Traditional Cardiac Exercise Rehabilitation Program in Patients With Chronic Heart Failure: a Randomized Controlled Study

TypeinterventionalSponsorUniversity Hospital, Clermont-FerrandRan2018 to 2022Enrolled23ConditionsChronic Heart Failure Patient, Rehabilitation ProgramArmsEccentric rehabilitation sessions
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Guillaume Plaquevent-Hostache *Cardiology and Vascular Diseases, Medical Clinic of Cardio-Pneumology of Durtol, Durtol, France.
Julianne Touron *UMR1019 INRA-UCA, ASMS team, CRNH Auvergne, INRA Centre Auvergne Rhone Alpes, Clermont Ferrand, France.
Frédéric CostesUMR1019 INRA-UCA, ASMS team, CRNH Auvergne, INRA Centre Auvergne Rhone Alpes, Clermont Ferrand, France.
Hélène PerraultFaculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada.
Guillaume ClerfondDepartment of Cardiology, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France.
Christine CueninCardiology and Vascular Diseases, Medical Clinic of Cardio-Pneumology of Durtol, Durtol, France.
Andreea MoisaCardiology and Vascular Diseases, Medical Clinic of Cardio-Pneumology of Durtol, Durtol, France.
Bruno PereiraDelegation to Clinical Research and Innovation, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France.
Marie-Claire BoiteuxCardiology and Vascular Diseases, Medical Clinic of Cardio-Pneumology of Durtol, Durtol, France.
Romain EschalierDepartment of Cardiology, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France.
Ruddy RichardUMR1019 INRA-UCA, ASMS team, CRNH Auvergne, INRA Centre Auvergne Rhone Alpes, Clermont Ferrand, France ruddy.richard@uca.fr.
Centre de Recherche en Nutrition Humaine d'Auvergne · FRCentre Hospitalier Universitaire de Clermont-Ferrand · FRUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionExercise-based rehabilitation is a standard feature of chronic heart failure management. The effectiveness of eccentric exercise could offer new opportunities for better tailoring rehabilitation programme to patients' limitations. The goal of the study is to contrast the impact of a mixed eccentric and concentric cycling training programme, to that of conventional concentric cycling rehabilitation in patients with chronic heart failure (peak oxygen consumption (VO METHODS AND ANALYSIS: It is a prospective, open, controlled and randomised study (2×25 subjects) carried out in a single centre. Subjects will perform five exercise sessions per week per the randomisation outcome, with the intervention group performing eccentric in three of the five weekly sessions while the control group will perform the five sessions of concentric exercise. Cycling intensity will be the same in both groups and fixed to the power associated with the first ventilatory threshold. Self-management education programme, callisthenics sessions and muscle strength trainings will also be carried out as for any heart failure patient normally included in the rehabilitation programme. The primary outcome will be the change in distance covered during the 6 min walk test. Secondary outcomes will include other physical mobility parameters, functional exercise capacities, quality of life and body composition as well as skeletal muscle properties including mitochondrial function parameters. ETHICS AND DISSEMINATION: The study has been approved by the institutional ethics review board (17.079) and the French regulatory authority for research (2017-A00969-44). Adverse events that could occur during the protocol will be reported to the principal investigator. The results will be published in an international peer-reviewed journal. TRIAL REGISTRATION NUMBER: NCT03716778.

Indexed as

Quality of LifeCardiac RehabilitationChronic DiseaseCost-Benefit AnalysisExercise TherapyHeart FailureHumansPatient ComplianceProspective StudiesRandomized Controlled Trials as TopicResistance TrainingWalk Testcardiac failurechronic diseaseexercise trainingfunctional capacities

Identifiers

PMID31558450
PMCPMC6773335
OpenAlexW2976455328

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.