Evidence map›Paper›PMID 31558180›Full record

Trial reportOncology research2020

Efficacy and Safety of Drug-Eluting Beads Transarterial Chemoembolization by CalliSpheres

Junhui Sun, Guanhui Zhou, Xiaoxi Xie, Wenjiang Gu, Jing Huang, Dedong Zhu, Wenhao Hu, Qinming Hou, Changsheng Shi, Tiefeng Li and 23 more

Open access · hybridAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Oncology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

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  5. Comparison of CalliSpheresRadiology and oncology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 19 institutions in 1 country.

Junhui SunHepatobiliary and Pancreatic Interventional Treatment Center, Division of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang UniversityHangzhouP.R. China.
Guanhui ZhouHepatobiliary and Pancreatic Interventional Treatment Center, Division of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang UniversityHangzhouP.R. China.
Xiaoxi XieInterventional Center, Xinchang People's HospitalShaoxingP.R. China.
Wenjiang GuDepartment of Intervention, Jiaxing Second HospitalJiaxingP.R. China.
Jing HuangDepartment of Hepatobiliary Surgery, Ningbo Medical Center, Lihuili Eastern HospitalNingboP.R. China.
Dedong ZhuDepartment of Liver Oncology, Ningbo No. 2 HospitalNingboP.R. China.
Wenhao HuDepartment of Intervention, The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouP.R. China.
Qinming HouDepartment of Radiology, Xixi Hospital of Hangzhou, Hangzhou 6th People's HospitalHangzhouP.R. China.
Changsheng ShiDepartment of Intervention, The Third Affiliated Hospital of Wenzhou Medical UniversityRuianP.R. China.
Tiefeng LiDepartment of Radiology, Beilun District People's Hospital of NingboNingboP.R. China.
Xin ZhangDepartment of Radiology, The First Affiliated Hospital, College of Medicine, Zhejiang UniversityHangzhouP.R. China.
Wenbin JiDepartment of Radiology, Taizhou Hospital of Zhejiang ProvinceLinhaiP.R. China.
Shihong YingDepartment of Radiology, The First Affiliated Hospital, College of Medicine, Zhejiang UniversityHangzhouP.R. China.
Zhiyi PengDepartment of Radiology, The First Affiliated Hospital, College of Medicine, Zhejiang UniversityHangzhouP.R. China.
Jian ZhouDepartment of Radiology, Hangzhou Cancer HospitalHangzhouP.R. China.
Zhihai YuDepartment of Vascular and Interventional Radiology, The Affiliated Hospital of Medical College of Ningbo UniversityNingboP.R. China.
Jiansong JiDepartment of Radiology, Lishui Central Hospital, Lishui Hospital of Zhejiang University, The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishuiP.R. China.
Haijun DuDepartment of Intervention, Dong Yang People's HospitalDongyangP.R. China.
Xiaohua GuoDepartment of Intervention, Jinhua Central HospitalJinhuaP.R. China.
Jian FangDepartment of Hepatobiliary Surgery, Quzhou People's HospitalQuzhouP.R. China.
Jun HanDepartment of Intervention, Jiaxing First HospitalJiaxingP.R. China.
Huanhai XuDivision of Digestive Endoscopy, YueQing City People's HospitalYueqingP.R. China.
Zhichao SunDepartment of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhouP.R. China.
Wenqiang YuDepartment of Intervention, Zhejiang Provincial People's HospitalHangzhouP.R. China.
Guoliang ShaoDepartment of Intervention, Zhejiang Cancer HospitalHangzhouP.R. China.
Xia WuDepartment of Radiology, Sir Run Run Shaw Hospital, Zhejiang University College of MedicineHangzhouP.R. China.
Hongjie HuDepartment of Radiology, Sir Run Run Shaw Hospital, Zhejiang University College of MedicineHangzhouP.R. China.
Ling LiDepartment of Intervention, The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouP.R. China.
Jiaping ZhengDepartment of Intervention, Zhejiang Cancer HospitalHangzhouP.R. China.
Jun LuoDepartment of Intervention, Zhejiang Cancer HospitalHangzhouP.R. China.
Yutang ChenDepartment of Intervention, Zhejiang Cancer HospitalHangzhouP.R. China.
Guohong CaoDepartment of Radiology, Shulan (Hangzhou) Hospital, Zhejiang University International HospitalHangzhouP.R. China.
Tingyang HuDepartment of Intervention, Zhejiang Provincial People's HospitalHangzhouP.R. China.
Zhejiang University · CNZhejiang Cancer Hospital · CNWenzhou Medical University · CNFirst Hospital of Jiaxing · CNSir Run Run Shaw Hospital · CNZhejiang Provincial People's Hospital · CNFirst Affiliated Hospital of Wenzhou Medical University · CNHangzhou Cancer Hospital · CNHangzhou Xixi hospital · CNJinhua Central Hospital · CNNingbo Medical Center Lihuili Hospital · CNNingbo No. 2 Hospital · CNNingbo University · CNQuzhou City People's Hospital · CNRuian People's Hospital · CNUniversity of Nottingham Ningbo China · CNYueqing People's Hospital · CNZhejiang Chinese Medical University · CNZhejiang Taizhou Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to investigate the efficacy and safety of drug-eluting beads transarterial chemoembolization (DEB-TACE) treatment in Chinese hepatocellular carcinoma (HCC) patients and the prognostic factors for treatment response as well as survival. A total of 275 HCC patients were included in this prospective study. Treatment response was assessed by modified Response Evaluation Criteria in Solid Tumors (mRECIST), and progression-free survival (PFS) as well as overall survival (OS) were determined. Liver function and adverse events (AEs) were assessed before and after DEB-TACE operation. Complete response (CR), partial response (PR), and objective response rate (ORR) were 22.9%, 60.7%, and 83.6%, respectively. The mean PFS was 362 (95% CI: 34.9-375) days, the 6-month PFS rate was 89.4 ± 2.1%, while the mean OS was 380 (95% CI: 370-389) days, and the 6-month OS rate was 94.4 ± 1.7%. Multivariate logistic regression revealed that portal vein invasion (

Indexed as

AgedAntineoplastic AgentsBilirubinCarcinoma, HepatocellularChemoembolization, TherapeuticChinaCreatinineDoxorubicinDrug Delivery SystemsEpirubicinFemaleHumansLiver NeoplasmsMaleMicrospheresMiddle AgedAntineoplastic AgentsBilirubinCreatinineDoxorubicinEpirubicinSerum Albumin, Human

Identifiers

PMID31558180
PMCPMC7851504
OpenAlexW2975602780

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.