ArticleTherapeutic advances in respiratory disease
Fatigue is highly prevalent in patients with COPD and correlates poorly with the degree of airflow limitation.
Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.
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Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effectiveness of non-pharmacological interventions for fatigue in adults with long-term conditions: a synopsis of the EIFFEL mixed-methods evidence synthesis.Health technology assessment (Winchester, England) · 2026Pooled it
- Gait differences between COPD and healthy controls: systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2024Pooled it
- The prevalence and related factors of fatigue in patients with COPD: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2021Pooled it
- Clinical Features Associated With Fatigue in People With Fibrotic Interstitial Lung Disease: Cross-Sectional Study.Respirology (Carlton, Vic.) · 2025Trial
- Real-Time Symptom Ratings Using Ecological Momentary Assessment Versus Traditional Questionnaires in Patients With Chronic Obstructive Pulmonary Disease: Observational Study.JMIR medical informatics · 2026Observational
- Effectiveness of non-pharmacological interventions for fatigue in long term conditions: systematic review and network meta-analysis.BMJ medicine · 2026Article
- Bidirectional Associations Between Physical Activity, Sedentary Behavior, and Daily Symptoms in Patients With Chronic Obstructive Pulmonary Disease: Longitudinal Observational Study.JMIR mHealth and uHealth · 2025Observational
- Associated factors of fatigue in patients with COPD: results from the FAntasTIGUE study.ERJ open research · 2025Article
- Evaluation of fatigue levels of individuals with chronic diseases: from the perspective of student nurses and patients.BMC nursing · 2025Article
- The impact of bronchoscopic lung volume reduction with endobronchial valves with or without pulmonary rehabilitation on symptoms of fatigue, anxiety and depression: a multicentre randomised controlled trial.ERJ open research · 2025Article
- Post-stroke fatigue: The role of comorbidities and its impact on quality of life.BMC neurology · 2025Article
- The relationship between fatigue levels and psychosocial adjustment in elderly individuals with chronic obstructive pulmonary disease: A descriptive study.Irish journal of medical science · 2025Article
- Fatigue Related COPD From Patient's Perspectives.Journal of evaluation in clinical practice · 2025Review
- Palliative Care for Patients with Severe Chronic Lung Diseases: A Swiss Position Paper.Respiration; international review of thoracic diseases · 2025Review
- Community led lung health support groups: processes, perspectives and roles for researchers.Breathe (Sheffield, England) · 2025Article
- Pharmacotherapy from Pre-COVID to Post-COVID: Longitudinal Trends and Predictive Indicators for Long COVID Symptoms.Biomedicines · 2024Article
- Changes in fatigue symptoms following an exercise-based rehabilitation programme for patients with long COVID.ERJ open research · 2024Article
- Unravelling the complex interplay of factors behind exercise limitations and physical inactivity in COPD.Breathe (Sheffield, England) · 2024Review
- Influencing factors of good quality of life among chronic obstructive pulmonary disease patients living in Zhejiang Province, China.Scientific reports · 2024Article
- ERS International Congress 2023: highlights from the Allied Respiratory Professionals Assembly.ERJ open research · 2024Article
Corrections and comments
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Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of this study was to compare fatigue levels between subjects with and without COPD, and to investigate the relationship between fatigue, demographics, clinical features and disease severity.
methodsA total of 1290 patients with COPD [age 65 ± 9 years, 61% male, forced expiratory volume in 1 s (FEV1) 56 ± 19% predicted] and 199 subjects without COPD (age 63 ± 9 years, 51% male, FEV1 112 ± 21% predicted) were assessed for fatigue (Checklist Individual Strength-Fatigue), demographics, clinical features and disease severity.
resultsPatients with COPD had a higher mean fatigue score, and a higher proportion of severe fatigue (CIS-Fatigue score 35 ± 12
conclusionsSevere fatigue is prevalent in half of the patients with COPD, and correlates poorly with the degree of airflow limitation. Future studies are needed to better understand the physical, psychological, behavioural, and systemic factors that precipitate or perpetuate fatigue in COPD.
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