ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020
Cortical microinfarcts in memory clinic patients are associated with reduced cerebral perfusion.
Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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Who cites it
28 citing papers in PubMed, 51 citations in OpenAlex.
- Association of Left Ventricular Function With Cerebral Small Vessel Disease and Cognition.Journal of the American Heart Association · 2026Article
- Border-associated macrophages: an emerging perspective from physiological basis and multi-disease roles to the mechanism of vascular cognitive impairment and dementia.Journal of neuroinflammation · 2025Review
- Motor-cognitive aging: The role of motor cortex and its pathways.NeuroImage · 2025Article
- Dynamic PET imaging in patients with unilateral carotid occlusion shows lateralized cerebral hypoperfusion, but no amyloid binding.Journal of Alzheimer's disease : JAD · 2025Article
- Associations between potential risk factors and blood-brain barrier water permeability in middle-aged and older adults.Journal of Alzheimer's disease : JAD · 2025Article
- Cross-Sectional Association Between Left Ventricular Geometric Patterns, Cortical Cerebral Microinfarcts, and Cognition.Journal of the American Heart Association · 2025Article
- The expression and association of MATK in chronic hypoperfusion patients with white matter hyperintensity.Frontiers in aging neuroscience · 2025Article
- Essential New Complexity-Based Themes for Patient-Centered Diagnosis and Treatment of Dementia and Predementia in Older People: Multimorbidity and Multilevel Phenomenology.Journal of clinical medicine · 2024Review
- Nimodipine Protects Vascular and Cognitive Function in an Animal Model of Cerebral Small Vessel Disease.Stroke · 2024Article
- Cortical microinfarcts in adults with Down syndrome assessed with 3T-MRI.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Progressive Disruption of Sphingosine-1-Phosphate Receptor 1 Correlates with Blood-Brain Barrier Leakage in A Rat Model of Chronic Hypoxic Hypoperfusion.Aging and disease · 2024Article
- Review
- Recent advances in arterial spin labeling perfusion MRI in patients with vascular cognitive impairment.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Review
- The Impact of Cortical Cerebral Microinfarcts on Functional Outcomes in Patients With Ischemic Stroke.Brain & NeuroRehabilitation · 2022Article
- Hemodynamic changes and neuronal damage detected by 9.4 T MRI in rats with chronic cerebral ischemia and cognitive impairment.Brain and behavior · 2022Article
- The role of inflammasomes in vascular cognitive impairment.Molecular neurodegeneration · 2022Review
- Traumatic Brain Magnetic Resonance Imaging Feature Extraction Based on Variable Model Algorithm in Stroke Examination.Contrast media & molecular imaging · 2022Article
- BYHW Decoction Improves Cognitive Impairments in Rats with Cerebral Microinfarcts via Activation of the PKA/CREB Pathway.Oxidative medicine and cellular longevity · 2022Article
- Cortical cerebral microinfarcts on 7T MRI: Risk factors, neuroimaging correlates and cognitive functioning - The Medea-7T study.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Cerebral cortical microinfarcts in patients with internal carotid artery occlusion.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
Corrections and comments
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Authors and funding
11 authors at 7 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebral cortical microinfarcts (CMIs) are small ischemic lesions associated with cognitive impairment and dementia. CMIs are frequently observed in cortical watershed areas suggesting that hypoperfusion contributes to their development. We investigated if presence of CMIs was related to a decrease in cerebral perfusion, globally or specifically in cortex surrounding CMIs. In 181 memory clinic patients (mean age 72 ± 9 years, 51% male), CMI presence was rated on 3-T magnetic resonance imaging (MRI). Cerebral perfusion was assessed from cortical gray matter of the anterior circulation using pseudo-continuous arterial spin labeling parameters
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.