Evidence map›Paper›PMID 31558103›Full record

ArticlePerspectives on psychological science : a journal of the Association for Psychological Science2020

The E Is in the G: Gene-Environment-Trait Correlations and Findings From Genome-Wide Association Studies.

Reut Avinun

Abstract read
In one paragraph

Article in Perspectives on psychological science : a journal of the Association for Psychological Science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  17. From Genome-Wide to Environment-Wide: Capturing the Environome.Perspectives on psychological science : a journal of the Association for Psychological Science · 2022
    Article
  18. Article
  19. Discrimination and anxiety: Using multiple polygenic scores to control for genetic liability.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  20. Vitamin D polygenic score is associated with neuroticism and the general psychopathology factor.Progress in neuro-psychopharmacology & biological psychiatry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Reut AvinunDepartment of Psychology & Neuroscience, Duke University.ORCID 0000-0002-3281-1268

Funding

Quantifying Individual Differences in Midlife Structural Brain Integrity Associated with Later AD/ADRD RiskR01AG049789 · NIA · DUKE UNIVERSITY · PI AHMAD R. HARIRI, TERRIE E MOFFITT · 2015 to 2026
$10.6M
NIA NIH HHS R01 AG049789
6 · The paper itself

Abstract

Genome-wide association studies (GWASs) have shown that pleiotropy is widespread (i.e., the same genetic variants affect multiple traits) and that complex traits are polygenic (i.e., affected by many genetic variants with very small effect sizes). However, despite the growing number of GWASs, the possible contribution of gene-environment correlations (rGEs) to pleiotropy and polygenicity has been mostly ignored. rGEs can lead to environmentally mediated pleiotropy or

Indexed as

Gene-Environment InteractionGenetic PleiotropyGenome-Wide Association StudyMental DisordersMultifactorial InheritanceHumansenvironmentgene–environment correlation (rGE)genome-wide association studymediated pleiotropypleiotropypolygenic risk scoressingle-nucleotide polymorphism (SNP)

Identifiers

PMID31558103
PMCPMC6980468

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.