Evidence map›Paper›PMID 31557883›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Toxicological Assessment of ITER-Like Tungsten Nanoparticles Using an In Vitro 3D Human Airway Epithelium Model.

Isabelle George, Chiara Uboldi, Elodie Bernard, Marcos Sanles Sobrido, Sarah Dine, Agnès Hagège, Dominique Vrel, Nathalie Herlin, Jerome Rose, Thierry Orsière and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. The potential adverse human health effects of metal-containing nanoparticles: a scoping review.Journal of occupational medicine and toxicology (London, England) · 2025
    Review
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  10. Simultaneous removal of harmful anions from geothermal waters using OHEnvironmental science and pollution research international · 2021
    Article
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  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Isabelle GeorgeCEA, SCBM, Université Paris Saclay, 91191 Gif-sur-Yvette, France. isabellegeorge87@gmail.com.
Chiara UboldiAix Marseille Univ, Avignon Université, CNRS, IRD, IMBE, 13005 Marseille, France. chiara.uboldi@imbe.fr.ORCID 0000-0002-5470-1705
Elodie BernardCEA, IRFM, F-13108 Saint Paul lez Durance, France. elodie.bernard@cea.fr.
Marcos Sanles SobridoCNRS, Aix Marseille Univ, IRD, INRA, Coll France, CEREGE, 13545, Aix en Provence, France. msanles@irec.cat.
Sarah DineUniversité Paris 13, Sorbonne Paris Cité; Laboratoire des Sciences des Procédés et des Matériaux, UPR 3407-CNRS, 99 avenue J.-B. Clément 93430 Villetaneuse, France. sarah.dine@lspm.cnrs.fr.
Agnès HagègeUniversité de Lyon, CNRS, Université Claude Bernard Lyon I, Institute of Analytical Sciences (ISA), UMR 5280, 5, rue de la Doua, 69100 Villeurbanne, France. Agnes.HAGEGE@isa-lyon.fr.
Dominique VrelUniversité Paris 13, Sorbonne Paris Cité; Laboratoire des Sciences des Procédés et des Matériaux, UPR 3407-CNRS, 99 avenue J.-B. Clément 93430 Villetaneuse, France. dominique.vrel@lspm.cnrs.fr.
Nathalie HerlinNIMBE, IRAMIS, Université Paris Saclay, 91191 Gif sur Yvette CEDEX, France. nathalie.herlin@cea.fr.
Jerome RoseCNRS, Aix Marseille Univ, IRD, INRA, Coll France, CEREGE, 13545, Aix en Provence, France. rose@cerege.fr.
Thierry OrsièreAix Marseille Univ, Avignon Université, CNRS, IRD, IMBE, 13005 Marseille, France. thierry.orsiere@imbe.fr.
Christian GrisoliaCEA, IRFM, F-13108 Saint Paul lez Durance, France. christian.grisolia@cea.fr.
Bernard RousseauCEA, SCBM, Université Paris Saclay, 91191 Gif-sur-Yvette, France. bernard.rousseau@cea.fr.
Véronique MalardAix Marseille Univ, CEA, CNRS, BIAM, UMR7265, EIPM, F-13108 Saint Paul-Lez-Durance, France. veronique.malard@cea.fr.ORCID 0000-0002-0020-0518
Centre National de la Recherche Scientifique · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRUniversité Claude Bernard Lyon 1 · FRUniversité Paris-Saclay · FR

Funding

Agence Nationale de la Recherche ANR-11-IDEX-0001-02Commissariat à l'Énergie Atomique et aux Énergies Alternatives Programme transverse de toxicologie
6 · The paper itself

Abstract

The International Thermonuclear Experimental Reactor (ITER) is an international project aimed at the production of carbon-free energy through the use of thermonuclear fusion. During ITER operation, in case of a loss-of-vacuum-accident, tungsten nanoparticles (W-NPs) could potentially be released into the environment and induce occupational exposure via inhalation. W-NPs toxicity was evaluated on MucilAir™, a 3D in vitro cell model of the human airway epithelium. MucilAir™ was exposed for 24 h to metallic ITER-like milled W-NPs, tungstate (WO

Indexed as

acute toxicitylungMucilAir™nanoparticlestungsten

Identifiers

PMID31557883
PMCPMC6836029
OpenAlexW2976887516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.