ArticleInternational journal of molecular sciences2019
NET4 Modulates the Compactness of Vacuoles in
Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 27 citations in OpenAlex.
- The Tonoplast Topology Index-a new metric for describing vacuole organization.Plant methods · 2026Article
- Salicylic acid inhibits V-ATPase activity and restricts cell elongation.Plant physiology · 2025Article
- SOS2 phosphorylates FREE1 to regulate multi-vesicular body trafficking and vacuolar dynamics under salt stress.The Plant cell · 2025Article
- The fate and function of theFrontiers in plant science · 2025Article
- NET4 and RabG3 link actin to the tonoplast and facilitate cytoskeletal remodelling during stomatal immunity.Nature communications · 2023Article
- Identification of Candidate Genes Involved in the Determinism of Pollen Grain Aperture Morphology by Comparative Transcriptome Analysis in Papaveraceae.Plants (Basel, Switzerland) · 2023Article
- At the Nexus between Cytoskeleton and Vacuole: How Plant Cytoskeletons Govern the Dynamics of Large Vacuoles.International journal of molecular sciences · 2023Review
- Fine mapping and candidate gene analysis of gynoecy trait in chieh-qua (Frontiers in plant science · 2023Article
- Membrane contact sites and cytoskeleton-membrane interactions in autophagy.FEBS letters · 2022Review
- Kinase Hog1 and Adr1 Opposingly Regulate Haploid Cell Morphology by Controlling Vacuole Size inJournal of fungi (Basel, Switzerland) · 2022Article
- A glossary of plant cell structures: Current insights and future questions.The Plant cell · 2022Review
- Plant cell mechanobiology: Greater than the sum of its parts.The Plant cell · 2022Review
- Vacuoles in Bryophytes: Properties, Biogenesis, and Evolution.Frontiers in plant science · 2022Review
- Vacuolar occupancy is crucial for cell elongation and growth regardless of the underlying mechanism.Plant signaling & behavior · 2021Article
- The TOR-Auxin Connection Upstream of Root Hair Growth.Plants (Basel, Switzerland) · 2021Review
- Bundling up the Role of the Actin Cytoskeleton in Primary Root Growth.Frontiers in plant science · 2021Review
- CTP Synthase 2 FromFrontiers in plant science · 2021Article
- It's Morphin' time: how multiple signals converge on ARF transcription factors to direct development.Current opinion in plant biology · 2020Review
- To Lead or to Follow: Contribution of the Plant Vacuole to Cell Growth.Frontiers in plant science · 2020Review
- Plant NETWORKED and VAP27 Proteins Work in Complexes to Regulate Membrane-Based Functions.Contact (Thousand Oaks (Ventura County, Calif.))Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
The dimension of the plants largest organelle-the vacuole-plays a major role in defining cellular elongation rates. The morphology of the vacuole is controlled by the actin cytoskeleton, but molecular players remain largely unknown. Recently, the Networked (NET) family of membrane-associated, actin-binding proteins has been identified. Here, we show that NET4A localizes to highly constricted regions of the vacuolar membrane and contributes to vacuolar morphology. Using genetic interference, we found that deregulation of NET4 abundance increases vacuolar occupancy, and that overexpression of NET4 abundance decreases vacuolar occupancy. Our data reveal that NET4A induces more compact vacuoles, correlating with reduced cellular and organ growth in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.