Evidence map›Paper›PMID 31557799›Full record

ArticleInternational journal of environmental research and public health2019

The Role of the Activation of the TRPV1 Receptor and of Nitric Oxide in Changes in Endothelial and Cardiac Function and Biomarker Levels in Hypertensive Rats.

Juan Carlos Torres-Narváez, Israel Pérez-Torres, Vicente Castrejón-Téllez, Elvira Varela-López, Víctor Hugo Oidor-Chan, Verónica Guarner-Lans, Álvaro Vargas-González, Raúl Martínez-Memije, Pedro Flores-Chávez, Etzna Zizith Cervantes-Yañez and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Chronic L-Name-Treatment Produces Hypertension by Different Mechanisms in Peripheral Tissues and Brain: Role of Central eNOS.Pathophysiology : the official journal of the International Society for Pathophysiology · 2020
    Article
  12. Article
  13. TRPC and TRPV Channels' Role in Vascular Remodeling and Disease.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Juan Carlos Torres-NarváezDepartamento de Farmacología "Dr. Rafael Méndez Martínez", Instituto Nacional de Cardiología "Ignacio Chávez", 14080 Tlalpan, CDMX, Mexico. juancarlostn63@hotmail.com.
Israel Pérez-TorresDepartamento de Patología, Instituto Nacional de Cardiología "Ignacio Chávez", 14080 Tlalpan, CDMX, Mexico. pertorisr@yahoo.com.mx.ORCID 0000-0001-6510-2954
Vicente Castrejón-TéllezDepartamento de Fisiología Celular, Instituto Nacional de Cardiología "Ignacio Chávez", 14080 Tlalpan, CDMX, Mexico. vcastrejn@yahoo.com.mx.
Elvira Varela-LópezLaboratorio de Cardiología Traslacional, Instituto Nacional de Cardiología "Ignacio Chávez", 14080 Tlalpan, CDMX, Mexico. varelopz@yahoo.com.
Víctor Hugo Oidor-ChanDepartamento de Farmacología "Dr. Rafael Méndez Martínez", Instituto Nacional de Cardiología "Ignacio Chávez", 14080 Tlalpan, CDMX, Mexico. victorhugooidor@gmail.com.
Verónica Guarner-LansDepartamento de Fisiología Celular, Instituto Nacional de Cardiología "Ignacio Chávez", 14080 Tlalpan, CDMX, Mexico. gualanv@yahoo.com.ORCID 0000-0002-2655-7590
Álvaro Vargas-GonzálezDepartamento de Fisiología Celular, Instituto Nacional de Cardiología "Ignacio Chávez", 14080 Tlalpan, CDMX, Mexico. varalv@cardiologia.org.mx.
Raúl Martínez-MemijeDepartamento de Instrumentación Electromecánica, Instituto Nacional de Cardiología "Ignacio Chávez", 14080 Tlalpan, CDMX, Mexico. raulmmemije@yahoo.com.
Pedro Flores-ChávezDepartamento de Instrumentación Electromecánica, Instituto Nacional de Cardiología "Ignacio Chávez", 14080 Tlalpan, CDMX, Mexico. pelfoch07@yahoo.com.mx.
Etzna Zizith Cervantes-YañezDepartamento de Sistemas Biológicos, Universidad Autónoma Metropolitana Unidad Xochimilco, 04960 Coyoacán, CDMX, Mexico. zizithcervantes@hotmail.com.
Claudia Angélica Soto-PeredoDepartamento de Sistemas Biológicos, Universidad Autónoma Metropolitana Unidad Xochimilco, 04960 Coyoacán, CDMX, Mexico. casoto@correo.xoc.uam.mx.
Gustavo Pastelín-HernándezDepartamento de Farmacología "Dr. Rafael Méndez Martínez", Instituto Nacional de Cardiología "Ignacio Chávez", 14080 Tlalpan, CDMX, Mexico. pastelingustavo@gmail.com.
Leonardo Del Valle-MondragónDepartamento de Farmacología "Dr. Rafael Méndez Martínez", Instituto Nacional de Cardiología "Ignacio Chávez", 14080 Tlalpan, CDMX, Mexico. leonardodvm65@hotmail.com.ORCID 0000-0002-2999-1050
Instituto Nacional de Cardiología · MXUniversidad Autónoma Metropolitana · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the present study was to analyze the actions of transient receptor potential vanilloid type 1 (TRPV1) agonist capsaicin (CS) and of its antagonist capsazepine (CZ), on cardiac function as well as endothelial biomarkers and some parameters related with nitric oxide (NO) release in

Indexed as

AnimalsBiomarkersBiopterinsBlood PressureCapsaicinDrug Evaluation, PreclinicalHeartHypertensionMaleMyocardiumNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide Synthase Type IIIOxidative StressProto-Oncogene Proteins c-aktRatsBiomarkersBiopterinsCapsaicincapsazepineNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide Synthase Type IIIProto-Oncogene Proteins c-aktsapropterinTrpv1 protein, ratTRPV1 receptorTRPV Cation ChannelscapsaicincapsazepinehypertensionL-NAMEnitric oxideTRPV1

Identifiers

PMID31557799
PMCPMC6801429
OpenAlexW2977167184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.